Results 101 to 110 of about 1,561,159 (250)

Dosimetric characterization of an intensity-modulated X-ray brachytherapy system

Journal of Medical Physics, 2018
Purpose: An intensity-modulated X-ray brachytherapy system is being developed for various clinical applications. This new system makes it possible for clinical staff to control energy as well as dose rate for different tumor sites according to their ...
Sung-Woo Lee, Evgeny Sozontov, Emil Strumban, Fang-Fang Yin   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Whole-ventricular irradiation for intracranial germ cell tumors: Dosimetric comparison of pencil beam scanned protons, intensity-modulated radiotherapy and volumetric-modulated arc therapy [PDF]

, 2019
Background: Whole-ventricular radiotherapy (WV-RT) followed by a boost to the tumor bed (WV-RT/TB) is recommended for intracranial germ cell tumors (IGCT).
Daniel M. Aebersold, Ahlhelm, Frank, Evelyn Herrmann, Antunes Correia, Dora Gabriela, Werner Volken, Dario Terribilini, Stieb, Sonja, Terribilini, Dario, Aebersold, Daniel, Manser, Peter, Peter Manser, Zepter, Stefan, Nicola Bizzocchi, Frank Ahlhelm, Dora Correia, Pica, Alessia, Stefan Zepter, Michael K. Fix, Sonja Stieb, Herrmann, Evelyn, Bizzocchi, Nicola, Weber, Damien Charles, Alessia Pica, Fix, Michael, Damien C. Weber, Volken, Werner   +25 more
core   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Observation of Intensity-Modulated Radiotherapy with Different Fractionated Doses Used in 58 Cases with Astrocytoma

Cancer Biology & Medicine, 2010
OBJECTIVE To analyze the therapeutic effects and side effects of intensity-modulated radiotherapy (IMRT) with different fractionated doses in treating astrocytoma.
Yun-qin LIU, Li-ting QIAN, Hong-yan ZHANG   +2 more
doaj   +1 more source

BPSK subcarrier intensity modulated free-space optical communications in atmospheric turbulence [PDF]

, 2009
Free-space optical communications (FSO) propagated over a clear atmosphere suffers from irradiance fluctuation caused by small but random atmospheric temperature fluctuations.
Ghassemlooy, Zabih, Popoola, Wasiu Oyewole, Popoola, Wasiu O., Ghassemlooy , Zabih   +3 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Long-Term Patient-Reported Bowel and Urinary Quality of Life in Patients Treated with Intensity-Modulated Radiotherapy Versus Intensity-Modulated Proton Therapy for Localized Prostate Cancer

Current Oncology
Purpose: This study aimed to compare long-term patient-reported outcomes in bowel and urinary domains between intensity-modulated radiotherapy (IMRT) and intensity-modulated proton therapy (IMPT) for localized prostate cancer.
Kimberly R. Gergelis, Miao Bai, Jiasen Ma, David M. Routman, Bradley J. Stish, Brian J. Davis, Thomas M. Pisansky, Thomas J. Whitaker, Richard Choo   +8 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Intensity-Modulated Photocurrent Spectroscopy Measurements of High-Efficiency Perovskite Solar Cells

Frequency domain characterization has long served as an important method for the examination of diverse kinetic processes that occur in solar cells. In this study, we investigated the dynamic response of high-efficiency perovskite solar cells utilizing ...
Zhaoning Song (1361256), Yanfa Yan (1281642), Behrang H. Hamadani (2300134), Sheng Fu (247124), Ganga R. Neupane (17721813), Susanna M. Thon (1596325)   +5 more
core   +1 more source