Results 51 to 60 of about 1,561,159 (250)

Performance of BPSK subcarrier intensity modulation free-space optical communications using a log-normal atmospheric turbulence model [PDF]

, 2010
In this paper, we present simulation results for the bit error rate (BER) performance and the fading penalty of a BPSK - subcarrier intensity modulation (BPSK-SIM) free-space optical (FSO) communication link in a log-normal atmospheric turbulence model ...
S. S. Muhammad, Z. Ghassemlooy, E. Leitgeb, Tang, Xuan, Muhammad, Sajid Sheikh, S. Rajbhandari, Ghassemlooy, Zabih, Popoola, Wasiu Oyewole, W. O. Popoola, Kandus, Gorazd, Leitgeb, Erich, Rajbhandari, Sujan, X. Tang, G. Kandus   +13 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Case Report: Dose-escalated volumetric modulated arc therapy achieving bowel and renal protection for large retroperitoneal inflammatory myofibroblastic tumor invading ureter and inferior vena cava

Frontiers in Oncology
Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm for which definitive radiotherapy in the retroperitoneum remains largely undefined, particularly when dose escalation must be balanced against the preservation of adjacent critical ...
Jiarui Zhang, Tianhao Liu, Cuihua Zhang, Siming Shi, Peng Zhen, Fang Fang   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Evaluation of Dosimetric Efficacy of RapidArc and Intensity-modulated Radiation Therapy Techniques in Head-and-Neck Cancers

Journal of Medical Physics
Aim: This study aims to compare the dosimetric efficacy of RapidArc (RA) and intensity-modulated radiation therapy (IMRT) in the treatment of head-and-neck cancer, focusing on treatment efficiency and organ at risk (OAR) dose.
Pratibha Singh, Manoj Kumar Singh, Atul Mishra   +2 more
doaj   +1 more source

Ninety-degree angled collimator: a dosimetric study related to dynamic intensity-modulated radiotherapy in patients with endometrial carcinoma

BMC Cancer, 2023
Background Our purpose was to ensure that the dose constraints of the organs at risk (OARs) were not exceeded while increasing the prescription dose to the planning target volume (PTV) from 45 to 50.4 Gray (Gy) with the dynamic intensity-modulated ...
Alparslan Serarslan, Yalçın Daştan, Telat Aksu, Rana Elif Yıldız, Bilge Gürsel, Deniz Meydan, Nilgün Özbek Okumuş   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The cost effectiveness of intensity-modulated radiation therapy and three-dimensional conformal radiotherapy in the treatment of head and neck cancers

Radiation Oncology, 2023
Purpose Intensity-modulated radiotherapy is developed as a replacement for 3-dimensional conformal radiation therapy. Considering the difference in costs and effectiveness of these interventions, the aim of this study was to compare the cost ...
Mehdi Varmaghani, Malihe Amiri, Hossein Ebrahimpour, Roham Salek, Javad Javan-Noughabi   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source