Results 171 to 180 of about 53,742 (305)

THE COMPARATIVE EFFECTIVENESS OF INTENSITY-MODULATED RADIOTHERAPY (IMRT) IN CANCER TREATMENT: SYSTEMATIC REVIEW

Intensity-Modulated Radio Therapy (IMRT) are often used to treat cancer because of its advantages and low risks. This study aims to investigate the evidence supporting the routine use of IMRT in various cancer in the aspects of conformity and homogeneity
Nazhifah, Naurah, Nurhidayat, Wahyudi
core  

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Imaging dose in image-guided radiotherapy for localized prostate intensity-modulated radiotherapy: a nationwide survey in Japan. [PDF]

J Radiat Res
Kito S, Takizawa T, Tanabe S, Suda Y, Nagahata T, Tohyama N, Okamoto H, Kodama T, Fujita Y, Miyashita H, Shinoda K, Kurooka M, Shimizu H, Ohno T, Sakamoto M.   +14 more
europepmc   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Effect of Multi-Leaf Collimator Angle Optimization on the Planning Parameters in Intensity-Modulated Radiotherapy for Thoracic Tumors. [PDF]

Technol Cancer Res Treat
Deng CY, Cai JH, Zhang JY, Lu JY.
europepmc   +1 more source

Comparison of RapidArc and static gantry intensity-modulated radiotherapy for nasopharyngeal carcinoma

, 2010
Objective: RapidArc (Varian Medical Systems, Palo Alto, CA) is a new volumetric-modulated arc radiotherapy technique with continuous modulation of gantry speed, dose rate, and multileaf collimator shape.
Cheng, H. C., Chan, C. L., Ngan, K. C., Cheung, W. K., Lee, K. H., Cheung, C. H.   +5 more
core  

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Various buildup-bolus regimens in post-mastectomy intensity modulated radiotherapy : dosimetric and radiobiological evaluation. [PDF]

Radiat Environ Biophys
Niu R, Tao F, Guo Q, Tao N, Wei X, Dai Z, Dai T, Wei X, Zhang J, Liu T, Gao L, Qi Y, Peng Q, Wen F.   +13 more
europepmc   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Prospective study on dose escalation using intensity modulated radiotherapy (IMRT) with simultaneous integrated boost (SIB) and concurrent chemotherapy in preoperative locally advanced rectal cancer. [PDF]

Rep Pract Oncol Radiother
Samanta S, Chatterjee K, Chatterjee S, Hossain ST, Basu S.   +4 more
europepmc   +1 more source