Results 211 to 220 of about 162,915 (338)

Analysis of the effect of dual reference lines on first positioning accuracy in intensity-modulated radiotherapy for cervical cancers. [PDF]

J Appl Clin Med Phys
Feng J, Shang Z, Ge B, Chu K, Jin J, Shao J, Zhang X.   +6 more
europepmc   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Imaging dose in image-guided radiotherapy for localized prostate intensity-modulated radiotherapy: a nationwide survey in Japan. [PDF]

J Radiat Res
Kito S, Takizawa T, Tanabe S, Suda Y, Nagahata T, Tohyama N, Okamoto H, Kodama T, Fujita Y, Miyashita H, Shinoda K, Kurooka M, Shimizu H, Ohno T, Sakamoto M.   +14 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Comparison of Local Control and Toxicity in T4 Nasopharyngeal Carcinoma Patients Treated with Induction Chemotherapy and Intensity-Modulated Radiotherapy: Conventional vs. Hyperfractionated Regimens. [PDF]

Medicina (Kaunas)
Hsieh HY, Lin JC, Chang HH.
europepmc   +1 more source

Sexual quality of life following prostate intensity modulated radiation therapy (IMRT) with a rectal/prostate spacer: Secondary analysis of a phase 3 trial [PDF]

, 2018
Bosch, Walter, Chundury, Anupama, et al,, Fischer-Valuck, Benjamin W, Gay, Hiram A, Michalski, Jeff   +5 more
core   +1 more source

Prospective Preference Assessment of Patients' Willingness to Participate in a Randomized Controlled Trial of Intensity Modulated Radiotherapy versus Proton Therapy for Localized Prostate Cancer [PDF]

, 2011
Arpita Shah, J.A. Efstathiou, Jonathan J. Paly, Scott D. Halpern, John P. Christodouleas, Curtiland Deville, Neha Vapiwala, A.L. Zietman, S.M. Hahn, Justin E. Bekelman   +9 more
openalex   +1 more source

Validation of the 8th Edition of the UICC/AJCC Staging System for Nasopharyngeal Carcinoma From Endemic Areas in the Intensity-Modulated Radiotherapy Era.

The Journal of the National Comprehensive Cancer Network, 2017
Ling-Long Tang, Yupei Chen, Y. Mao, Zixian Wang, R. Guo, Lei Chen, L. Tian, A. Lin, Li Li, Ying Sun, Jun Ma   +10 more
semanticscholar   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

A robust optimization model for intensity-modulated radiotherapy: Cheap-Minimax. [PDF]

Med Phys
Sevilla AC, Cabal G, Wahl N, Puerta ME, Rivera JC.   +4 more
europepmc   +1 more source