Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li+14 more
wiley +1 more source
Dosimetric and Radiobiological Impact of Patient Setup Errors in Intensity-modulated Radiotherapy for Esophageal Cancer. [PDF]
Cai JH, Peng X, Lu JY.
europepmc +1 more source
Forward-planning intensity-modulated radiotherapy technique for prostate cancer [PDF]
Mohamed Metwaly+3 more
openalex +1 more source
A Fe (III)–Pt (II) porphyrin framework‐based radiosensitizer (FPTM‐LP) is constructed to serve as an oxygen economizer, hypoxia self‐monitoring device, and reactive oxygen species (ROS) amplifier. The glutathione (GSH)/pH‐responsive release of lonidamine achieves oxygen‐economization to combat hypoxia‐induced radioresistance guided by near infrared ...
Shiye Du+9 more
wiley +1 more source
Remarkable Response to Radiotherapy With Simultaneous Integrated Boost Intensity-Modulated Radiotherapy for Locally Advanced Lymphoepithelial Carcinoma of the Hypopharynx in a Nonagenarian. [PDF]
Katano A, Sawayanagi S, Yamashita H.
europepmc +1 more source
Adjuvant whole abdominal intensity modulated radiotherapy (IMRT) for high risk stage FIGO III patients with ovarian cancer (OVAR-IMRT-01) – Pilot trial of a phase I/II study: study protocol [PDF]
Nathalie Rochet+8 more
openalex +1 more source
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou+12 more
wiley +1 more source
Efficacy and safety of simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative chemotherapy treatment of multifocal high-grade glioma. [PDF]
Jiang N, Xu LP, Li F, Wang PP, Cao Y.
europepmc +1 more source
Influence of Intensity-Modulated Radiotherapy on Acute Genitourinary and Gastrointestinal Toxicity in the Treatment of Localized Prostate Cancer [PDF]
Ashesh B. Jani+2 more
openalex +1 more source
The role of splicing factor 3A subunit 3 (SF3A3) in driving endometrial cancer (EC) progression and potential therapeutic interventions. SF3A3, a core component of the U2 small nuclear ribonucleoprotein (U2 snRNP), is upregulated in endometrial cancer (EC) and promotes tumor growth and cisplatin resistance. RNA‐binding protein immunoprecipitation (RIP)
Wei Yu+13 more
wiley +1 more source