Results 241 to 250 of about 162,915 (338)

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Intensity-modulated radiotherapy with carbon ion boost for high-risk sinonasal squamous cell carcinoma: clinical outcomes and the management of the node-negative neck. [PDF]

Clin Transl Radiat Oncol
Bauer L, Weusthof K, Regnery S, Deng M, Schröter P, Stritzke F, Netzer N, Franke H, Uzun-Lang K, Moratin J, Ristow O, Thoelken R, Harrabi SB, Herfarth K, Adeberg S, Debus J, Held T.   +16 more
europepmc   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Actor critic with experience replay-based automatic treatment planning for prostate cancer intensity modulated radiotherapy. [PDF]

Med Phys
Abrar MM, Sapkota P, Sprouts D, Jia X, Chi Y.   +4 more
europepmc   +1 more source

T4/N2 classification nasopharyngeal carcinoma benefit from concurrent chemotherapy in the era of intensity-modulated radiotherapy

, 2016
Ruifei Xie, Bing Xia, Xuebang Zhang, Wei Hu, Ruping Zhao, Congying Xie, Jianhua Wang, Ni Zhang, Shixiu Wu   +8 more
openalex   +2 more sources

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Impact of Neoadjuvant and Adjuvant Pleural Intensity-Modulated Radiotherapy in Multimodality Treatment for Malignant Pleural Mesothelioma. [PDF]

Thorac Cancer
Mosleh B, Schwarz S, Cho A, Sinn K, Steindl A, Zöchbauer-Müller S, Köstler WJ, Dieckmann K, Heilmann M, Widder J, Gompelmann D, Aigner C, Klikovits T, Hoda MA.   +13 more
europepmc   +1 more source

Bone density and pain response following intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for vertebral metastases - secondary results of a randomized trial [PDF]

, 2018
Tanja Sprave, Vivek Verma, Robert Förster, Ingmar Schlampp, Katharina Hees, Thomas Brückner, Tilman Bostel, Rami A. El Shafie, Thomas Welzel, Nils H. Nicolay, Jürgen Debus, Harald Rief   +11 more
openalex   +1 more source

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

Advanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo, Deyi Yang, Mingpu Yang, Jue Wang, Dingfeng Zhang, Daoming Zhu, Qingyong Xu, Yanni Song   +7 more
wiley   +1 more source

Observation of the effect of intensity-modulated radiotherapy combined with microwave diathermy on tumor marker levels and prognosis in cervical cancer. [PDF]

Front Med (Lausanne)
Liu X, Li W, Zhou J.
europepmc   +1 more source