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Rectal Radiotherapy — Intensity-modulated Radiotherapy Delivery, Delineation and Doses

Clinical Oncology, 2016
The use of intensity-modulated radiotherapy in rectal cancer is attractive in that it may reduce acute and late toxicities and potentially facilitate dose escalation. Intensity-modulated radiotherapy probably has a role in selected patients, but further investigation is required to identify the parameters for selection.
S, Teoh, R, Muirhead
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Intensity modulation methods for proton radiotherapy

Physics in Medicine and Biology, 1999
The characteristic Bragg peak of protons or heavy ions provides a good localization of dose in three dimensions. Through their ability to deliver laterally and distally shaped homogenous fields, protons have been shown to be a precise and practical method for delivering highly conformal radiotherapy.
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Gradients and intensity modulated radiotherapy

Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2002
A consequence of the advent of intensity modulated radiation therapy (IMRT) is the presence of large dose gradients surrounding the tumor, and the regions at risk (RAR's) near the tumor. Unlike standard radiotherapy, these gradients are not the chance result of a few beam choices, but rather they are strategically placed by the optimization software. A
J.M. Kapatoes   +5 more
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Quality assurance of intensity-modulated radiotherapy

Seminars in Radiation Oncology, 2002
Intensity-modulated radiation therapy (IMRT) requires the use of inverse treatment planning and nonuniform fluence beams delivered by a series of complex radiation portals. The quality assurance procedures for conventional three-dimensional conformal radiation therapy (3D-CRT) have been developed and are in worldwide clinical use, but the more complex ...
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Exploration of tradeoffs in intensity-modulated radiotherapy

Physics in Medicine and Biology, 2005
The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and we apply it to explore the tradeoff ...
David, Craft   +2 more
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Hardware-sensitive optimization for intensity modulated radiotherapy

Physics in Medicine and Biology, 2000
The multileaf collimator (MLC) hardware constraints are usually neglected in the process of intensity-modulated beam optimization. Consequently, it is not always possible to deliver planned beam modulation using dynamic MLC. Beam optimization is significantly diminished if the results must be approximated due to limitations imposed by the delivery ...
P S, Cho, R J, Marks
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Intensity-modulated radiotherapy of the female breast

Medical Dosimetry, 2002
Current methods for intensity-modulated radiotherapy (IMRT) in breast cancer use forward planning based on equivalent radiological path length to design intensity modulated tangential beams. Compared to conventional tangential techniques, dose reduction of organs at risk is limited using these techniques.
Christoph, Thilmann   +10 more
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Intensity-modulated radiotherapy: Is xerostomia still prevalent?

Current Oncology Reports, 2005
Conformal radiation with intensity-modulated radiotherapy (IMRT) is a technique that potentially can minimize the dose to salivary glands and thereby decrease the incidence of xerostomia. Precise target determination and delineation is most important when using salivary gland-sparing techniques of IMRT.
Mark S, Chambers   +9 more
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Intensity-Modulated Radiotherapy – Technology and Clinical Applications

Oncology Research and Treatment, 2002
Intensity-modulated radiotherapy (IMRT) is one of the most important developments in radiooncology of the last years. As an extension of 3D conformal radiotherapy, it provides the possibility of delivering a high radiation dose to the tumor tissue, protecting radiosensible critical organs nearby or even surrounded by the target. This is realized by the
B H, Didinger, W, Schlegel, J, Debus
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Clinical use of intensity-modulated radiotherapy: part II

The British Journal of Radiology, 2004
Intensity-modulated radiotherapy (IMRT) is a novel conformal radiotherapy technique which is gaining increasing clinical use worldwide. This article aims to summarize the published data pertaining to clinical indications of this therapy for head and neck, central nervous system, and lung tumours. The main indications in head and neck cancer are parotid
M T, Guerrero Urbano, C M, Nutting
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