Results 51 to 60 of about 349,914 (309)
IET Nanodielectrics, 2021 This work presents a new approach for the design of an FMF with a Gaussian core and a trench in the cladding. For the proposed few‐mode fibre (FMF), Fused Silica (SiO2) is considered as a host‐material, whereas Germanium Oxide(GeO2) and Fluorine(F)are ...
Bhagyalaxmi Behera +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Compact Low-Loss Electroabsorption Modulator Using a Graphene-Inserted Metal-Slot-Added Waveguide
IEEE Access, 2020 Metal slots have been used to obtain strong light-graphene interaction, which usually requires them to be a few tens of nanometers wide. However, narrow metal slot waveguides have a large intrinsic loss; they are not efficiently connected to conventional
Jihoon Seo, Min-Suk Kwon
doaj +1 more source
Power Efficient Subcarrier Modulation for Intensity Modulated Channels
Optics Express, 2010 We compare formats for optical intensity modulation limited by thermal noise with the assumption of having ideal devices. At the same bitrate and bandwidth, a hitherto unknown format turns out to be more power efficient than known formats. This new modulation, which is a hybrid between on-off keying and phase-shift keying, belongs to the subcarrier ...
Johnny, Karout +2 more
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Photonics, 2019 Colour-shift keying (CSK) is a visible light communication (VLC) modulation scheme used in the existing IEEE 802.15.7 standard. In CSK, information is transmitted by changing the light intensities of the RGB LEDs.
Roger Alexander Martínez-Ciro +3 more
doaj +1 more source