Results 141 to 150 of about 3,925,241 (306)

Additional file 1 of Implementing palliative care in intensive care units: assessing processes using the normalisation process theory NoMAD instrument

Supplementary Material 1.
Meddick-Dyson, Stephanie A., Finch, Tracy, Boland, Jason W., Pearson, Mark, Bradshaw, Andy, Murtagh, Fliss E. M.   +5 more
openaire   +1 more source

A reduction relation for which postponement of K-contractions, Conservation and Preservation of Strong Normalisation hold

, 1996
Postponement of fi K -contractions and the conservation theorem do not hold for ordinary fi but have been established by de Groote for a mixture of fi with another reduction relation.
Of Strong Normalisation, Fairouz Kamareddine   +1 more
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Polypharmacy as an ordered indicator of therapeutic complexity in a national cardiovascular prevention programme

Frontiers in Pharmacology
BackgroundThe prevalence of polypharmacy has been rising worldwide, most studies focuses on older adults. However, little is known about patterns and determinants of polypharmacy in middle-aged individuals engaged in structured national prevention ...
Jacek Gonos, Marek Tradecki, Marek Tradecki, Grzegorz Kubielas, Grzegorz Kubielas, Ercole Vellone, Ercole Vellone, Olga Fedorowicz, Michał Czapla, Michał Czapla, Michał Czapla, Bartosz Uchmanowicz   +11 more
doaj   +1 more source

Carotid plaque dynamic contrast-enhanced magnetic resonance imaging normalised signal intensity reproducibly differs between plaque and vessel wall

ABSTRACT Background Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables non-invasive characterization of carotid atherosclerotic plaque. Purpose To evaluate the performance and reproducibility of a simplified DCE-
Thomas Readford, Gonzalo J Martínez, Sanjay Patel, Peter L. Kench, Marcelo Andía, Martin Ugander, Nicola Giannotti   +6 more
openaire   +2 more sources

Normalisation in Weakly Orthogonal Rewriting

, 1999
. A rewrite sequence is said to be outermost-fair if every outermost redex occurrence is eventually eliminated. Outermost-fair rewriting is known to be (head-)normalising for almost orthogonal rewrite systems.
Vincent van Oostrom
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Forecast errors and monetary policy normalisation in the euro area. Bruegel Policy Contribution Issue n˚24 | December 2018 [PDF]

, 2018
What did we learn from the recent monetary policy normalisation experiences of Sweden, the United States and the United Kingdom? Zsolt Darvas consider the lessons and analyse the European Central Bank’s forecasting track record and possible factors that ...
Darvas, Zsolt
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source