Results 91 to 100 of about 3,650,640 (366)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Flavored circular collider: cornering New Physics at FCC-ee via flavor-changing processes

European Physical Journal C: Particles and Fields
We illustrate the potential of a future high-intensity $$e^+ e^-$$ e + e - collider running at the Z pole in probing extensions of the Standard Model via precise measurements of flavor-changing processes.
Lukas Allwicher, Gino Isidori, Marko Pesut   +2 more
doaj   +1 more source

Extremely high-intensity laser interactions with fundamental quantum systems [PDF]

, 2011
The field of laser-matter interaction traditionally deals with the response of atoms, molecules, and plasmas to an external light wave. However, the recent sustained technological progress is opening up the possibility of employing intense laser ...
A. Piazza, C. Müller, K. Hatsagortsyan, C. Keitel   +3 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

The future prospects of muon colliders and neutrino factories

, 2019
The potential of muon beams for high energy physics applications is described along with the challenges of producing high quality muon beams. Two proposed approaches for delivering high intensity muon beams, a proton driver source and a positron driver ...
Boscolo, Manuela, Delahaye, Jean Pierre, Palmer, Mark   +2 more
core   +1 more source

Roadmap of ultrafast x-ray atomic and molecular physics

, 2018
X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past ...
L. Young, K. Ueda, M. Gühr, P. Bucksbaum, M. Simon, S. Mukamel, N. Rohringer, K. Prince, C. Masciovecchio, M. Meyer, A. Rudenko, D. Rolles, C. Bostedt, M. Fuchs, D. Reis, R. Santra, H. Kapteyn, M. Murnane, H. Ibrahim, F. Légaré, M. Vrakking, M. Isinger, D. Kroon, M. Gisselbrecht, A. L’Huillier, H. Wörner, S. Leone   +26 more
semanticscholar   +1 more source

New opportunities at the next-generation neutrino experiments I: BSM neutrino physics and dark matter

Reports on progress in physics. Physical Society, 2020
The combination of the high intensity proton beam facilities and massive detectors for precision measurements of neutrino oscillation parameters including the charge-parity violating (CPV) phase will open the door to help make beyond the standard model ...
C. Argüelles, A. Aurisano, B. Batell, J. Berger, M. Bishai, T. Boschi, N. Byrnes, A. Chatterjee, A. Chodos, T. Coan, Y. Cui, A. de Gouvêa, P. Denton, A. De Roeck, W. Flanagan, D. V. Forero, R. Gandrajula, A. Hatzikoutelis, M. Hostert, B. Jones, B. Kayser, K. Kelly, D. Kim, J. Kopp, A. Kubik, K. Lang, I. Lepetic, P. Machado, C. Moura, F. Olness, J. Park, S. Pascoli, S. Prakash, L. Rogers, I. Safa, A. Schneider, K. Scholberg, S. Shin, I. Shoemaker, G. Sinev, B. Smithers, A. Sousa, Y. Sui, V. Takhistov, J. Thomas, J. Todd, Yu-Dai Tsai, Y. Tsai, J. Yu, C. Zhang   +49 more
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Precipitation Characteristics in the Community Atmosphere Model and Their Dependence on Model Physics and Resolution

Journal of Advances in Modeling Earth Systems, 2019
Precipitation amount (A), frequency (F), intensity (I), and duration (D) are important properties of precipitation, but their estimates are sensitive to data resolution.
Di Chen, Aiguo Dai
doaj   +1 more source