Results 81 to 90 of about 1,001,402 (281)

Coherently excited superresolution using intensity product of phase-controlled quantum erasers via polarization-basis projection measurements

Scientific Reports
Recently, the delayed-choice quantum eraser has been applied for coherently excited superresolution using phase-controlled projection measurements of laser light to overcome the diffraction limit in classical physics as well as to solve the limited order
Byoung S. Ham
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

ANALYSIS OF DIFFICULTY LEVEL OF PHYSICS NATIONAL EXAMINATION’S QUESTIONS

Jurnal Pendidikan IPA Indonesia, 2016
This study aimed to determine: (1) the difficulty level of items in physics National Exam of 2013 (2) physics materials that were difficult and very difficult.
Yusrizal Yusrizal
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Self-Trapping of Light Using the Pancharatnam-Berry Phase

Physical Review X, 2019
Since its introduction by Berry in 1984, the geometric phase has become of fundamental importance in physics, with applications ranging from solid-state physics to optics. In optics, the Pancharatnam-Berry phase allows the tailoring of optical beams by a
Chandroth P. Jisha, Alessandro Alberucci, Jeroen Beeckman, Stefan Nolte   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

High-intensity lasers and research activities in China

High Power Laser Science and Engineering
This paper provides an overview of the current status of ultrafast and ultra-intense lasers with peak powers exceeding 100 TW and examines the research activities in high-energy-density physics within China.
Yutong Li, Liming Chen, Min Chen, Feng Liu, Yuqiu Gu, Bing Guo, Jianfei Hua, Taiwu Huang, Yuxin Leng, Fei Li, Lu Li, Ruxin Li, Chen Lin, Wei Lu, Zhihui Lyu, Wenjun Ma, Xiaonan Ning, Yujie Peng, Yang Wan, Jinguang Wang, Zhaohua Wang, Zhiyi Wei, Xueqing Yan, Jie Zhang, Baozhen Zhao, Zengxiu Zhao, Cangtao Zhou, Kainan Zhou, Weimin Zhou, Jianqiang Zhu, Ping Zhu   +30 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source