Results 91 to 100 of about 1,001,402 (281)

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Recent progress in atomic and molecular physics for controlled fusion and astrophysics

open access: yesMatter and Radiation at Extremes, 2021
Stefan Weber, Yong Wu, Jianguo Wang
doaj   +1 more source

Identifying the electron–positron cascade regimes in high-intensity laser-matter interactions

open access: yesNew Journal of Physics, 2019
Strong-field quantum electrodynamics predicts electron-seeded electron–positron pair cascades when the electric field in the rest-frame of the seed electron approaches the Sauter–Schwinger field, i.e. $\eta ={E}_{{\rm{RF}}}/{E}_{S}\sim 1$ .
C Slade-Lowther   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

GANIL Status report

open access: yes, 2005
The GANIL-Spiral facility (Caen, France) is dedicated to the acceleration of heavy ion beams for nuclear physics, atomic physics, radiobiology and material irradiation.
Chautard, F.   +3 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Effects of Surface Layer Physics Schemes on the Simulated Intensity and Structure of Typhoon Rai (2021)

open access: yesAtmosphere
The influences of surface layer (SL) physics schemes on the simulated intensity and structure of Typhoon Rai (2021) are investigated using the WRF model.
Thi-Huyen Hoang   +2 more
doaj   +1 more source

Plasmonics in Nanoslit for Manipulation of Light

open access: yesIEEE Access, 2013
A nanoslit is capable of performing versatile functions in nanophotonic applications. In this invited paper, we discuss the physics and manipulation methods of surface plasmon excitation such as directional switching at a nanoslit. Furthermore, enhancing
Taerin Chung   +6 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

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