Results 81 to 90 of about 3,650,640 (366)

Optical Surface Vortices and Their Use in Nanoscale Manipulation [PDF]

, 2009
Following a brief overview of the physics underlying the interaction of twisted light with atoms at near-resonance frequencies, the essential ingredients of the interaction of atoms with surface optical vortices are described.
Andrews, D. L., Babiker, M., Lembessis, V. E.   +2 more
core   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

LIMpy: A Semianalytic Approach to Simulating Multiline Intensity Maps at Millimeter Wavelengths

The Astrophysical Journal, 2023
Mapping of multiple lines such as the fine-structure emission from [C ii ] (157.7 μ m), [O iii ] (52 and 88.4 μ m), and rotational emission lines from CO are of particular interest for upcoming line intensity mapping (LIM) experiments at millimeter ...
Anirban Roy, Dariannette Valentín-Martínez, Kailai Wang, Nicholas Battaglia, Alexander van Engelen   +4 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Neutrino lines from DM decay induced by high-scale seesaw interactions

Journal of High Energy Physics, 2021
If the stability of the dark matter (DM) particle is due to an accidental symmetry, nothing prevents UV physics from destabilising it by inducing DM decays suppressed by powers of the UV scale.
Rupert Coy, Thomas Hambye
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Learning science through a collaborative invention project in primary school

Disciplinary and Interdisciplinary Science Education Research, 2023
The study examines students’ disciplinary learning in physics and interdisciplinary science learning opportunities that students encounter during a collaborative invention project. Thirteen student teams (aged 11 to 12, N = 46) designed and constructed a
Kati Sormunen, Saara Vehmaa, Pirita Seitamaa-Hakkarainen, Jari Lavonen, Kai Hakkarainen, Kalle Juuti   +5 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Hanbury-Brown and Twiss Intensity Correlations of Parabosons

, 2006
This paper shows that in intensity correlation measurements there will be clear and unambiguous signals that new-physics particles are, or aren't, parabosons. For a parabosonic field in a dominant single-mode, there is a diagonal P-representation in the "
Alexander, Charles A. Nelson, Doplicher, Doplicher, Frascino, Fry, Glauber, Glauber, Glauber, Glauber, Glauber, Glauber, Goldhaber, Green, Greenberg, Greenberg, Greenberg, Greenberg, Hanbury-Brown, Hanbury-Brown, Jing, Klauder, Klauder, Klauder, Mukunda, Nelson, Ohnuki, Paresh R. Shimpi, Sharma, Sharma, Sudarshan, Tomasik, Volkov, Weiner   +33 more
core   +1 more source

Neutrinos and collider physics [PDF]

, 2015
We review the collider phenomenology of neutrino physics and the synergetic aspects at energy, intensity and cosmic frontiers to test the new physics behind the neutrino mass mechanism. In particular, we focus on seesaw models within the minimal setup as
F. Deppisch, P. Bhupal Dev, A. Pilaftsis
semanticscholar   +1 more source