Results 151 to 160 of about 270,776 (287)

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Pulmonary Peak Flow Assessment: An Easy Tool for Cardiac Output Estimation in Hemodynamically Stable Neonates

International Journal of Pediatrics
Angela Alfarano, Roberto Marzollo, Serena Amighetti, Cesare Tomasi, Maria Ilaria Bosio, Salvatore Aversa, Elena Borelli, Mario Motta, Francesco Maria Risso   +8 more
doaj   +1 more source

Protocol for developing a national approach to surveillance and prevention for neonatal ventilator-associated pneumonia. [PDF]

BMJ Paediatr Open
Li CZ, Tse-Chang A, Yoon EW, Paquette V, Roberts A, Afifi J, Yang CL, Khurshid F, Augustine S, Choudhury J, Elsharkawy A, Hamilton C, Hicks M, Joynt C, Wang D, Lee KS, Louis D, Robinson JL, Mohamed A, Mitra S, Shah VS, Srigley JA, Stavel M, Sherlock R, Wong J, Kuan MT, Madise-Wobo AD, Lemyre B, Joly C, Kharrat A, Gupta-Bhatnagar S, Zarembo M, Bacchini F, Beltempo M, Shah PS, Ting JY.   +35 more
europepmc   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Correction: The effect of peer-led education on the quality of life of mothers of premature infants in neonatal intensive care units: a quasi-experimental study. [PDF]

BMC Res Notes
Begjani J, Fomani FK, Beiranvand F, Rajabi MM.   +3 more
europepmc   +1 more source

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

British Journal of Clinical Pharmacology, EarlyView.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire, Sean Keane, Reya Vinay Shah, Toqa El‐Nahhas, Iao Lei, Salma Alamin, Niall Conlon, Dagan Osborne Lonsdale   +7 more
wiley   +1 more source

Extended NICUs or specialized pediatric networks? The need to reinforce centralized, multidisciplinary care - a comment on Decembrino et al. [PDF]

Ital J Pediatr
Brisca G, Ingelmo PM, Camporesi A, Di Nardo M, Dato A, Ricci Z, Bussolin L, Conti G, Tesoro S, Minardi C, Marinosci GZ, Wolfler A, Moscatelli A, Italian Society of Neonatal and Pediatric Anesthesia and Intensive Care (SARNePI).   +13 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Nurse staffing skill mix and acuity-adjusted provision ratios in Swedish neonatal care: A cohort benchmark study. [PDF]

Int J Nurs Stud Adv
Dillner P, Göransson KE, Norman M, Unbeck M, Förberg U.   +4 more
europepmc   +1 more source