While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Interfacility Variation in Diagnosis and Tocolysis for Threatened Preterm Labor and Its Association With Gestational Age Threshold for Neonatal Intensive Care Unit Admission: A Cross-Sectional Survey of Perinatal Centers in the Chugoku-Shikoku Region of Western Japan. [PDF]
Yamane N +9 more
europepmc +1 more source
Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul +7 more
wiley +1 more source
Competing Tensions: Nurse Perceptions of Family-Centered Care and Parents' Needs in Neonatal Care
Background: Family-centered care is founded upon collaboration between parents and healthcare professionals, caring for a child and parents as one entity.
Bloomer, Melissa +2 more
core +1 more source
Can PIM-3 score predict risk for neonatal mortality vs. SNAPPE II and SNAP II scores in a tertiary surgical neonatal intensive care unit? [PDF]
Atkinson R, Ray S, Hannam S, Chalia M.
europepmc +1 more source
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
The Ethics of Proximity: Bedside Ethics and the Contribution of NICU Nurses to Ethical Deliberation. [PDF]
Todini C +8 more
europepmc +1 more source
The impact of medication shortages on paediatric care: A retrospective impact analysis
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg +6 more
wiley +1 more source

