Results 171 to 180 of about 151,412 (312)

“You need to be supported”: An integrative review of nurses’ experiences after death in neonatal and paediatric intensive care

Background The death of a child can have a profound impact on critical care nurses, shaping their professional practice and personal lives in diverse, enduring ways.
Brooks, Laura, Bloomer, Melissa, Coventry, Alysia, Ranse, Kristen, Bloomer, Melissa J., Rowe, Jessie, Thomas, Shontelle, Brooks, Laura A., https://orcid.org/   +8 more
core   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Outcome and epilepsy following neonatal stroke in the Italian Registry of Infantile Thrombosis. [PDF]

Eur J Pediatr
Sartori S, Nosadini M, Brigiari G, Francavilla A, Foiadelli T, Veraldi D, Suppiej A, Bagna R, Casellato S, Cao V, Baggio L, Conti M, Farinasso D, Accorsi P, Cordelli DM, Magarotto M, Massoud M, Pegoraro V, Pelizza MF, Saracco P, Arena V, Ballardini E, Falcone A, Gaffuri M, Gentile D, Iodice A, Rosati A, Bugin S, Chiodin E, Fogliani V, Freschi P, Radicioni M, Cavaliere E, Toldo I, Ancona C, Capato L, Pin JN, Guidotti I, Lombardini M, Luciani M, Simioni P, R. I. T. I. Working group.   +41 more
europepmc   +1 more source

Manual of neonatal respiratory care /

, 2006
The Manual of Neonatal Respiratory Care offers a clear, clinical approach to all aspects of neonatal pulmonology! Access step-by-step guidance to normal lung development and physiology, cardiopulmonary assessment, neonatal respiratory failure, mechanical
Sinha, Sunil K.,M.D., Ph.D., Donn, Steven M.   +1 more
core  

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

H1N1-Related Hemophagocytic Lymphohistiocytosis Complicated by Severe Rhabdomyolysis in a Pediatric Patient: A First Case Report

Case Reports in Pediatrics
Lucia Marseglia, Antonella Gambadauro, Federica Xerra, Annalisa Cacciola, Immacolata Rulli, Valeria Chirico, Raffaella Mallamace, Eloisa Gitto   +7 more
doaj   +1 more source

The relationship of soluble urokinase plasminogen activator receptor levels with preterm premature rupture of membranes and predictive value in neonatal intensive care unit admission. [PDF]

Rev Assoc Med Bras (1992)
Koc BL, Tanacan A, Haliloglu E, Yilmaz HE, Ersak DT, Aktas BA, Kara O, Sahin D.   +7 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Summary of best evidence on parental involvement in neonatal intensive care units: integrating family-centered and family-integrated care models. [PDF]

Glob Health Action
He J, Chen N, He Y, Wang Q.
europepmc   +1 more source