Results 151 to 160 of about 4,926,102 (254)

The Incidence, Severity and Clinical Consequence of Left Pulmonary Artery Stenosis After PDA Device Closure in Premature Infants Less Than 2 Kilograms

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter patent ductus arteriosus (PDA) device closure is an effective treatment option for premature infants with hemodynamically significant PDA. Left pulmonary artery (LPA) stenosis has been reported as a complication, however there is limited data on risk factors, clinical significance, and long‐term outcomes.
Bryan Mosher   +7 more
wiley   +1 more source

A Case of Pallister–Killian Syndrome in a Newborn

open access: yesCase Reports in Genetics
Giulia Di Donato   +8 more
doaj   +1 more source

The Impact of Glycation on Protein Digestibility

open access: yesChemFoodChem, EarlyView.
Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann   +2 more
wiley   +1 more source

Newborn Early Warning Systems in Screening and Detection of Neonatal Emergencies: A Bibliometric Analysis. [PDF]

open access: yesNurs Crit Care
Wijaya E   +10 more
europepmc   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed   +5 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

From promise to practice: digital health through the lens of neonatal care. [PDF]

open access: yesLancet Reg Health Am
Variane GFT   +7 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara   +20 more
wiley   +1 more source

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