Results 71 to 80 of about 270,776 (287)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Peripheral perfusion index-reference range in healthy Portuguese term newborns

Journal of Pediatric and Neonatal Individualized Medicine, 2014
Introduction: Peripheral perfusion index (PPI) is a non-invasive numerical value of peripheral perfusion derived from a pulse oximeter signal. It has been suggested that PPI may be a valuable adjunct diagnostic tool to detect early clinically significant
Joana Jardim, Ruben Rocha, Gorett Silva, Hercília Guimarães   +3 more
doaj   +1 more source

Paediatric and neonatal intensive care [PDF]

Canadian Journal of Anaesthesia, 1988
The major objective of intensive care for infants and children is to provide maximum surveillance and support of organ systems during acute, but reversible, ]ire-threatening illness) In contrast to adult patients, there are fewer children admilted to intensive care unit~ (ICU's) who suffer from either chronic or degenerative organ system disorders ...
openaire   +2 more sources

Parents' consent to neonatal decisions about feeding and discharge [PDF]

, 2006
English law requires health care practitioners to obtain parents' consent before all touching of their child. However, nurses tend to leave doctors to request parents' consent to intensive care interventions, and it is generally assumed that before ...
Alderson, Priscilla
core   +1 more source

Clinical spectrum and outcomes of neonatal candidiasis in a tertiary care hospital in Karachi, Pakistan [PDF]

, 2011
Introduction: Candidal infections are a serious problem in neonatal intensive care units, increasing morbidity and mortality in low birth weight infants in addition to escalating health-care costs.
Ariff, Shabina, Sajjad, Reema, Saleem, Ali Faisal, Soofi, Sajid Bashir   +3 more
core   +2 more sources

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Flow-synchronized nasal intermittent positive pressure ventilation for prevention of extubation failure in neonates: a review of literature and a case series of neonates with congenital diaphragmatic hernia successfully managed with this strategy

Italian Journal of Pediatrics
Background Advances in neonatal medicine have improved survival rates in neonatal intensive care units, especially for high-complexity cases like congenital diaphragmatic hernia (CDH).
Sara Ronci, Stefano Caoci, Camilla Gizzi, Flaminia Calzolari, Irma Capolupo, Domenico Umberto De Rose, Chiara Maddaloni, Ludovica Martini, Ferdinando Savignoni, Corrado Moretti, Andrea Dotta   +10 more
doaj   +1 more source

Embryological development of the intestine and necrotizing enterocolitis

Journal of Pediatric and Neonatal Individualized Medicine, 2016
It is possible to distinguish two phases in the development and maturation of the intestine: intra-uterine and extra-uterine. Up until the 13th week of the embryological phase, a fetus’ development is not controlled by factors external to the alimentary
Anna De Magistris, Maria Antonietta Marcialis, Melania Puddu, Angelica Dessì, Roberta Irmesi, Elisabetta Coni, Vassilios Fanos   +6 more
doaj   +1 more source

Genotyping and antifungal susceptibility of Dipodascus capitatus isolated in a neonatal intensive care unit of a sicilian hospital [PDF]

, 2017
In August 2015, Dipodascus capitatus was isolated from two patients admitted to the neonatal intensive care unit. Nosocomial acquisition of the fungus was suspected and epidemiological studies were undertaken.
Aquilina, G., Cal\ue0, C., Capra, G., Corsello, G., Fasciana, T., Giammanco, A, Giuffr\ue8, M., Lipari, D., Pinello, G., Schierz, I.   +9 more
core   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source