Results 71 to 80 of about 635,322 (291)

Acute kidney injury in neonatal age

Journal of Pediatric and Neonatal Individualized Medicine, 2014
Acute kidney injury (AKI) is a pathology characterized by a sudden decrease in kidney function that results in the accumulation of nitrogenous waste products and alteration of the regulation of extracellular fluid volume, electrolytes, and acid-base ...
Giovanni Ottonello, Angelica Dessì, Paola Neroni, Maria Elisabetta Trudu, Danila Manus, Vassilios Fanos   +5 more
doaj   +1 more source

Reducing toxic stress in the neonatal intensive care unit to improve infant outcomes.

Nursing Outlook, 2019
In 2011, the American Academy of Pediatrics (AAP) published a technical report on the lifelong effects of early toxic stress on human development, and included a new framework for promoting pediatric health: the Ecobiodevelopmental Framework for Early ...
Ashley M. Weber, T. Harrison
semanticscholar   +1 more source

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

Advanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang, Mingjie Kuang, Jiacheng Shi, Ruiyan Li, Yuhan Zhang, Xinting Liu, Runtan Li, Yong Kang, Bin Yao, Shuquan Zhang, Xiaoyuan Ji   +10 more
wiley   +1 more source

Paediatric and neonatal intensive care [PDF]

Canadian Journal of Anaesthesia, 1988
The major objective of intensive care for infants and children is to provide maximum surveillance and support of organ systems during acute, but reversible, ]ire-threatening illness) In contrast to adult patients, there are fewer children admilted to intensive care unit~ (ICU's) who suffer from either chronic or degenerative organ system disorders ...
openaire   +2 more sources

Parental satisfaction with neonatal intensive care units: a quantitative cross-sectional study

BMC Health Services Research, 2019
BackgroundPatients and users experiences are useful for monitoring the quality of the hospital provisions and to improve health care delivery. Research results on associations between parental satisfaction and their socio-demographic status are ...
I. Hagen, V. Iversen, E. Nesset, R. Orner, M. Svindseth   +4 more
semanticscholar   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Peripheral perfusion index-reference range in healthy Portuguese term newborns

Journal of Pediatric and Neonatal Individualized Medicine, 2014
Introduction: Peripheral perfusion index (PPI) is a non-invasive numerical value of peripheral perfusion derived from a pulse oximeter signal. It has been suggested that PPI may be a valuable adjunct diagnostic tool to detect early clinically significant
Joana Jardim, Ruben Rocha, Gorett Silva, Hercília Guimarães   +3 more
doaj   +1 more source

Incidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates

Archives of Disease in Childhood: Fetal and Neonatal Edition, 2019
Objective To determine the incidence, indicators and clinical impact of difficult tracheal intubations in the neonatal intensive care unit (NICU). Design Retrospective review of prospectively collected data on intubations performed in the NICU from the ...
T. Sawyer, Elizabeth E. Foglia, A. Ades, A. Moussa, N. Napolitano, K. Glass, L. Johnston, Philipp Jung, Neetu Singh, B. H. Quek, James Barry, J. Zenge, S. Demeo, Brianna K. Brei, J. Krick, J. Kim, V. Nadkarni, A. Nishisaki   +17 more
semanticscholar   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source