Results 91 to 100 of about 1,041,138 (268)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Psychiatric intensive care accreditation: The development of AIMS-PICU [PDF]

, 2010
Stephen Dye, Matthew J. Page, Paul Deacon, Alan Metherall   +3 more
openalex   +1 more source

Adverse outcomes of delayed intensive care unit

, 2021
Fernanda Ribeiro Quintino Santos, Maurício de Nassau Machado, Suzana Margareth Lobo   +2 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Knowledge, Attitude, and Practice of Thrombolysis in Family Members of Cerebral Infarction Patients: Structural Equation Modeling Analysis

International Journal of General Medicine
Fan Huang,1,2 Ling Zhou,1,2 Ping Zhao,1,2 Meiping Guo,1,2 Wujia Chen1,2 1Intensive Care Unit, Wujin Hospital Affiliated with Jiangsu University, Changzhou, 213000, People’s Republic of China; 2The Wujin Clinical College of Xuzhou Medical University ...
Huang F, Zhou L, Zhao P, Guo M, Chen W
doaj  

The effect of peer-led education on the quality of life of mothers of premature infants in neonatal intensive care units: a quasi-experimental study [PDF]

Jamalodin Begjani, Fatemeh Khoshnavay Fomani, Farzane Beiranvand, Mohammad Mehdi Rajabi   +3 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

A Bibliometric Analysis of Medication Compliance in Children with Asthma

Journal of Multidisciplinary Healthcare
Jing Zhao,1 Yu Ding,1 Zhiyuan Wang,2 Guo Kou,1 Sen Xu,1 Jing Tai,1 Chunrui Zhang,1 Ying Guo,1 Jun Yang1 1Department of Pediatric Intensive Care, Nanyang Second People’s Hospital, Nanyang, Henan, 473012, People’s Republic of China; 2Department of ...
Zhao J, Ding Y, Wang Z, Kou G, Xu S, Tai J, Zhang C, Guo Y, Yang J   +8 more
doaj  

The Impact of Inadequate Terminal Disinfection on an Outbreak of Imipenem-Resistant Acinetobacter baumannii in an Intensive Care Unit

, 2014
Wei‐Lun Liu, Hsueh-Wen Liang, Mei-Feng Lee, Hsin-Lan Lin, Yu‐Hsiu Lin, Chi‐Chung Chen, Ping–Chin Chang, Chih‐Cheng Lai, Yin-Ching Chuang, Hung-Jen Tang   +9 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source