Results 121 to 130 of about 2,528,189 (360)

NOVEL MANAGEMENT OF DEPRESSION USING KETAMINE IN THE INTENSIVE CARE UNIT [PDF]

, 2021
Nirmaljot Kaur, Siva Naga S. Yarrarapu, Abhishek R. Giri, Kathleen A. Rottman Pietrzak, Christan D. Santos, Philip Lowman, Shehzad Niaz, Pablo Moreno Franco, Devang Sanghavi   +8 more
openalex   +1 more source

Intensive care [PDF]

BMJ, 2007
openaire   +2 more sources

Intensive Medical Care and Cardiovascular Disease Disability Reductions [PDF]

There is little empirical evidence to explain why disability declined among the elderly over the past 20 years. In this paper, we explore the role of improved medical care for cardiovascular disease on health status improvements over time.
David M. Cutler, Kate A. Stewart, Mary Beth Landrum   +2 more
core  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

BACTERIAL PROFILE AND THEIR ANTIBIOTIC RESISTANCE PATTERNS FROM BLOOD CULTURE AND ASSOCIATED RISK FACTORS IN INTENSIVE CARE UNIT AT THE UNIVERSITY OF GONDAR COMPREHENSIVE SPECIALIZED HOSPITAL, NORTHWEST ETHIOPIA

, 2021
Segen Tekle, Feleke Moges, Zemene Tigabu, Alem Getaneh   +3 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Systemic Inflammatory Response Index Has a Value for the Early Diagnosis and Short-Term Prognostic Assessment of Severe Pneumonia in the Elderly

Canadian Respiratory Journal
This article probed the value of systemic inflammatory response index (SIRI) in the early diagnosis and short-term prognostic assessment of severe pneumonia (SPM) in the elderly.
Xiao Xu, Huajuan Xu, Ming Li, Shuying Yan, Huilin Chen   +4 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Effects of HALP Score, C-Reactive Protein/Albumin Ratio, and Platelet/Lymphocyte Ratio on Predicting Mortality in Geriatric Patients in the Respiratory Intensive Care Unit

Clinical Interventions in Aging
Kamuran Uluç,1 Esra Akkütük Öngel,2 Şükran Merve Çolakoğlu,2 Nazan Köylü İlkaya,2 Özkan Devran,2 Ahmet Oğuzhan Küçük,3 Hatice Kutbay Özçelik2 1Department of Critical Care Medicine, University of Health Sciences ...
Uluç K, Akkütük Öngel E, Çolakoğlu ŞM, Köylü İlkaya N, Devran Ö, Küçük AO, Kutbay Özçelik H   +6 more
doaj  

Crew resource management training in the intensive care unit. A multisite controlled before–after study

, 2016
Peter Kemper, Martine C. de Bruijne, Cathy van Dyck, Ralph L So, Peter L. Tangkau, Cordula Wagner   +5 more
openalex   +2 more sources