Results 121 to 130 of about 2,458,151 (310)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A Bibliometric Analysis of Medication Compliance in Children with Asthma

open access: yesJournal of Multidisciplinary Healthcare
Jing Zhao,1 Yu Ding,1 Zhiyuan Wang,2 Guo Kou,1 Sen Xu,1 Jing Tai,1 Chunrui Zhang,1 Ying Guo,1 Jun Yang1 1Department of Pediatric Intensive Care, Nanyang Second People’s Hospital, Nanyang, Henan, 473012, People’s Republic of China; 2Department of ...
Zhao J   +8 more
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Latent profiles of compassion fatigue among clinical nurse preceptors and their associations with work alienation

open access: yesScientific Reports
This study aimed to investigate the latent profiles of clinical nurse preceptors (CNPs)’ compassion fatigue (CF), identify the influencing factors, and examine their association with work alienation.
Yuejun Huang   +3 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Multivariate Analysis of Shock Risk and Model Development and Validation in Elderly Patients Following Hip Fracture Surgery in the Intensive Care Unit (ICU): A Retrospective Cohort Study

open access: yesClinical Interventions in Aging
Xue Wang, Zhen Cui, Mengqi Tong, Miaomiao Yu, Ying Bai Department of Critical Care Medicine, Beijing Jishuitan Hospital Affiliated to Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Ying Bai, Department of ...
Wang X, Cui Z, Tong M, Yu M, Bai Y
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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