Results 71 to 80 of about 7,689,168 (361)

Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome

Critical Care, 2022
Background In the context of acute respiratory distress syndrome (ARDS), the response to lung recruitment maneuvers (LRMs) varies considerably from one patient to another and so is difficult to predict.
Yoann Zerbib, Alexis Lambour, Julien Maizel, Loay Kontar, Bertrand De Cagny, Thierry Soupison, Thomas Bradier, Michel Slama, Clément Brault   +8 more
doaj   +1 more source

Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol. [PDF]

, 2010
BACKGROUND: There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness.
A Ceriello, A Ceriello, A Ceriello, A Chiaretti, A Rovlias, A Russo, A Russo, AA Ferrando, AA Ferrando, Allan Goldman, Ann Truesdale, AP Furnary, AP Furnary, B Halverson-Steele, CK Rayner, Claire Snowdon, D Ardigo, D Ardigo, D Ardigo, D Field, DA Schoenfeld, DC Angus, DC Angus, Deborah Percy, Diana Elbourne, Duncan Macrae, Elizabeth Allen, EV Faustino, G Paret, G Van den Berghe, G Van den Berghe, Helen Betts, J Lacroix, JL Haybittle, JM Hoxworth, John Pappachan, K Esposito, K Katsura, K Malmberg, K Malmberg, Kevin Morris, KJ Jenkins, LM McManus, M Cornblath, MAQ Curley, Margrid Schindler, Mark Peters, MF Oliver, Michael Broadhead, MM Gearhart, NJ Hall, P Lange, PA Li, Paul Baines, Peter-Marc Fortune, R Peto, RE Anderson, RG Branco, Richard Grieve, Robert Tasker, Roger Parslow, S Leteurtre, S Yendamuri, SE Capes, SE Capes, Simon Nadel, Tara Quick, The Acute Respiratory Distress Syndrome Network, TM Vriesendorp, TN Pham, UN Das, UN Das, UN Das, V Srinivasan, WA Pulsinelli, WD Dietrich, Zdenek Slavik   +76 more
core   +5 more sources

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit

Open Forum Infectious Diseases, 2018
Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr, U. Jaschinski, X. Wittebole, T. Szakmany, J. Lipman, S. Ñamendys-Silva, I. Martín-Loeches, M. Leone, M. Lupu, J. Vincent   +9 more
semanticscholar   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Impact of exposure time in awake prone positioning on clinical outcomes of patients with COVID-19-related acute respiratory failure treated with high-flow nasal oxygen: a multicenter cohort study

Critical Care, 2022
Background In patients with COVID-19-related acute respiratory failure (ARF), awake prone positioning (AW-PP) reduces the need for intubation in patients treated with high-flow nasal oxygen (HFNO).
Mariano Esperatti, Marina Busico, Nora Angélica Fuentes, Adrian Gallardo, Javier Osatnik, Alejandra Vitali, Elizabeth Gisele Wasinger, Matías Olmos, Jorgelina Quintana, Santiago Nicolas Saavedra, Ana Inés Lagazio, Facundo Juan Andrada, Hiromi Kakisu, Nahuel Esteban Romano, Agustin Matarrese, Mariela Adriana Mogadouro, Giuliana Mast, Claudia Navarro Moreno, Greta Dennise Rebaza Niquin, Veronica Barbaresi, Alejandro Bruhn Cruz, Bruno Leonel Ferreyro, Antoni Torres, Argentine Collaborative Group on High Flow and Prone Positioning   +23 more
doaj   +1 more source

Trends and Variation in End-of-Life Care for Medicare Beneficiaries With Severe Chronic Illness [PDF]

, 2011
Provides an updated analysis of regional and hospital variations in end-of-life care for Medicare beneficiaries with chronic illnesses, including percentage of hospital deaths, days in intensive care units, and physician labor per ...
Amos R. Esty, Chiang-hua Chang Phd, David C. Goodman, Elliott S. Fisher, Kristen K. Bronner   +4 more
core   +1 more source

Psychiatric nurses’ views on criteria for psychiatric intensive care: acute and intensive care staff compared [PDF]

, 2003
Aim: To explore and investigate differences between the views of qualified nurses working in psychiatric intensive care units (PICUs) and acute care wards on which patients are appropriate for PICU care.
Allan, Basson, Beer, Brown, Clark, Dix, Eddie McCann, Holzworth, Jane Alexander, Jeffery, Lehane, Len Bowers, Michalon, Neil Crowhurst, Rachlin, Ryan, Sarah Eales, Smith, Stuart Guy, Werner   +19 more
core   +2 more sources

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness*

Critical Care Medicine, 2018
Objectives: To describe the frequency of co-occurring newly acquired cognitive impairment, disability in activities of daily livings, and depression among survivors of a critical illness and to evaluate predictors of being free of post-intensive care ...
A. Marra, P. Pandharipande, T. Girard, Mayur B. Patel, C. Hughes, J. Jackson, Jennifer L. Thompson, R. Chandrasekhar, E. W. Ely, N. Brummel   +9 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Mortality and quality of life in the five years after severe sepsis [PDF]

, 2013
Peer reviewedPublisher ...
Cuthbertson, Brian H, Elders, Andrew, Hall, Sally, Mackenzie, Simon J, Mackirdy, Fiona, Maclennan, Graeme, Taylor, Jane, the Scottish Critical Care Trials Group and the Scottish Intensive Care Society Audit Group   +7 more
core   +2 more sources