Results 81 to 90 of about 7,511,780 (403)

Providing intensive care [PDF]

BMJ, 1996
The recent deaths of two severely ill patients being transferred from one hospital to another in search of specialised intensive care have caused public alarm in Britain and have raised questions about the resourcing and organisation of adult and paediatric intensive care.
openaire   +3 more sources

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit

Open Forum Infectious Diseases, 2018
Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr, U. Jaschinski, X. Wittebole, T. Szakmany, J. Lipman, S. Ñamendys-Silva, I. Martín-Loeches, M. Leone, M. Lupu, J. Vincent   +9 more
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

M2c Macrophages Protect Mice from Adriamycin-Induced Nephropathy by Upregulating CD62L in Tregs

Mediators of Inflammation, 2022
Regulatory T cells (Tregs) and M2c macrophages have been shown to exert potentially synergistic therapeutic effects in animals with adriamycin-induced nephropathy (AN), a model chronic proteinuric renal disease.
Junyu Lu, Shengqiu Lv, Jielong Pang, Tao Qin, Yegui Yang, Weisheng Lu, Zhengzhao Li, Geng Yang, Jianfeng Zhang   +8 more
doaj   +1 more source

Antidepressant Use and Depressive Symptoms in Intensive Care Unit Survivors [PDF]

, 2017
Nearly 30% of intensive care unit (ICU) survivors have depressive symptoms 2-12 months after hospital discharge. We examined the prevalence of depressive symptoms and risk factors for depressive symptoms in 204 patients at their initial evaluation in the
Boustani, Malaz, Gao, Sujuan, Khan, Babar, Khan, Sikandar, Kheir, You Na, Kirk, Kayla, Lasiter, Sue, Mosher, Chris, Wang, Sophia   +8 more
core   +1 more source

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness*

Critical Care Medicine, 2018
Objectives: To describe the frequency of co-occurring newly acquired cognitive impairment, disability in activities of daily livings, and depression among survivors of a critical illness and to evaluate predictors of being free of post-intensive care ...
A. Marra, P. Pandharipande, T. Girard, Mayur B. Patel, C. Hughes, J. Jackson, Jennifer L. Thompson, R. Chandrasekhar, E. W. Ely, N. Brummel   +9 more
semanticscholar   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Effects of Erector Spinae Plane Block and Quadratus Lumborum Block on Postoperative Opioid Consumption in Laparoscopic Kidney Surgery: A Randomized Controlled Clinical Trial

Pain Research and Management
Trial Registration: ClinicalTrials.gov identifier ...
Skladzien Tomasz, Maciejewski Pawel, Cicio Michal, Wojciech Szpunar, Szpor Jan, Lonc Tomasz, Kwinta Anna, Bugielska Renata, Szkudlarek Olga, Drygalski Tomasz, Terlecki Michal   +10 more
doaj   +1 more source

Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE): protocol for a multicentre randomised controlled trial

Trials, 2023
Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length ...
Siebe G. Blok, Amne Mousa, Michelle G. Brouwer, Harm-Jan de Grooth, Ary Serpa Neto, Michiel J. Blans, Sylvia den Boer, Tom Dormans, Henrik Endeman, Timo Roeleveld, Harm Scholten, Eline R. van Slobbe-Bijlsma, Erik Scholten, Hugo Touw, Fleur Stefanie L. I. M. van der Ven, Evert-Jan Wils, David J. van Westerloo, Leo M. A. Heunks, Marcus J. Schultz, Frederique Paulus, Pieter R. Tuinman   +20 more
doaj   +1 more source