Results 111 to 120 of about 1,998,001 (374)

Adsorption therapy in critically ill with septic shock and acute kidney injury: a retrospective and prospective cohort study

Annals of Intensive Care, 2020
Background Haemoadsorption has been described as an effective way to control increased pro- and anti-inflammatory mediators (“cytokine storm”) in septic shock patients. No prospective or randomised clinical study has yet confirmed these results. However,
Gregor A. Schittek, Philipp Zoidl, Michael Eichinger, Simon Orlob, Holger Simonis, Martin Rief, Philipp Metnitz, Tobias Fellinger, Jens Soukup   +8 more
doaj   +1 more source

About adaptive state knowledge extraction for septic shock mortality prediction [PDF]

, 2010
The early prediction of mortality is one of the unresolved tasks in intensive care medicine. This contribution models medical symptoms as observations cased by transitions between hidden markov states.
Brause, Rüdiger W.
core  

INTCare: a knowledge discovery based intelligent decision support system for intensive care medicine [PDF]

, 2005
This paper introduces the INTCare system, an intelligent information system based on a completely automated Knowledge Discovery process and on the Agents paradigm.
Abelha S., Alvaro Silva, Barnato A., Buchanan B. G., Chang R., Claver E., Dietterich T., Dybowski R., Essex-Sorlie D., Fayyad U., Ferber J., Forgionne G. A., H D., Hanson C., Hayes-Roth B., Haykin S., Jennings R., José Neves, Kulikowski C. A., Lanzi P., Lavrac N., Lee S., Li L., Lopes Gomes, Lueg C., Manuel Filipe Santos, Michalowski W., Miranda D., Mora M., Musaev A., Paulo Cortez, Pedro Gago, Pople H. E., Prudsys A. G., Rosenschein S. J., Rumelhart D. E., Russel S., Santos M. F., Santos M. F., Santos M. F., Santos M. F., Silva A., Simon H., Suchman L., Turban E., Vicari R. M., Weiss G., Yim H. S.   +47 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Visual TASK: A Collaborative Cognitive Aid for Acute Care Resuscitation

, 2016
Preventable medical errors are a severe problem in healthcare, causing over 400,000 deaths per year in the US in hospitals alone. In acute care, the branch of medicine encompassing the emergency department (ED) and intensive care units (ICU), error rates
Calhoun, Aaron W., Gonzales, Michael J., Henry, Joshua M., Riek, Laurel D.   +3 more
core   +1 more source

Polyneuropathy in the critical ill patient: a common diagnosis in intensive care medicine? [PDF]

, 2006
BACKGROUND AND OBJECTIVES: The diffuse axonal polyneuropathy, more commonly known as Critical Illness Polyneuropathy (CIP), has been discussed by authors by decades; however, it has only been deeply studied over the last thirty years, becoming more ...
Cabral, Marcella M., Canineu, Rafael Fernando Brandão, Guimarães, Hélio Penna, Lopes, Antonio Carlos, Lopes, Renato Delascio, Saes, Letícia Sandre Vendrame   +5 more
core   +2 more sources

Experts’ guidelines of intubation and extubation of the ICU patient of French Society of Anaesthesia and Intensive Care Medicine (SFAR) and French-speaking Intensive Care Society (SRLF)

Annals of Intensive Care, 2019
BackgroundIntubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required in emergency situations for patients
H. Quintard, E. L’her, J. Pottecher, F. Adnet, J. Constantin, A. De Jong, P. Diemunsch, R. Fesseau, A. Freynet, C. Girault, C. Guitton, Y. Hamonic, É. Maury, A. Mekontso-Dessap, F. Michel, P. Nolent, S. Perbet, G. Prat, A. Roquilly, K. Tazarourte, N. Terzi, A. Thille, M. Alves, E. Gayat, L. Donetti   +24 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Sudden Onset of Coma and Fulminant Progression to Brain Death in a 48-Year-Old Male With Cerebral Malaria

Case Reports in Critical Care
Cerebral malaria is the most severe complication of Plasmodium falciparum infection. Left untreated, it is universally fatal. Coma is the clinical hallmark, emerging between the first and third days of fever.
Marina Costa, Cristiana Barbosa, Mauro Pereira, Luís Ribeiro, Pedro Silveira   +4 more
doaj   +1 more source

Statement paper on diversity for the European Society of Intensive Care Medicine (ESICM)

Intensive Care Medicine, 2019
IntroductionDiversity has become a key-strategic element of success in various political and economic fields. The European Society of Intensive Care Medicine (ESICM) decided to make diversity a key strategic priority for the future and appointed a Task ...
B. Weiss
semanticscholar   +1 more source