Results 171 to 180 of about 1,998,001 (374)

Elastase and its Inhibitors in Intensive Care Medicine [PDF]

, 1990
Fritz, Hans, Jochum, Marianne
core   +1 more source

Weaning from mechanical ventilation. When paediatric intensive care medicine profits from adult experience and vice-versa [PDF]

, 2001
Laurent Brochard
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Intensive care medicine/nutrition [PDF]

, 1994

openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Not everything possible will benefit a patient

Swiss Medical Weekly, 2015
Andreas Valentin
doaj   +1 more source

Comparison of airway opening pressure measurements: low-constant-flow vs. constant low-slope pressure ramp methods

BMC Anesthesiology
Background The airway closure phenomenon occurs when the airway collapses, isolating the proximal airway from the distal alveoli. Airway opening pressure (AOP) is required to reopen closed airways.
Ken Tonai, Atsuko Shono, Ryuichi Nakayama, Shinshu Katayama   +3 more
doaj   +1 more source

2010 Annual Evidence Update on Critical Illness Rehabilitation [PDF]

, 2010
For this annual evidence update a detailed literature review was undertaken to retrieve any evidence published subsequent to the literature search which formed the basis for the NICE guideline.
Gibson, Vanessa, Griffiths, John, Kishen, Roop, Morris, Craig, Parker, Robert, Treacher, David   +5 more
core  

Induced Hypothermia in Intensive Care Medicine [PDF]

, 1996
Stephen A. Bernard
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source