Results 31 to 40 of about 1,218,126 (318)

Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management

Critical Care, 2019
Dysphagia may present in all critically ill patients and large-scale clinical data show that e.g. post-extubation dysphagia (PED) is commonly observed in intensive care unit (ICU) patients.
P. Zuercher, C. Moret, R. Dziewas, J. Schefold   +3 more
semanticscholar   +1 more source

Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter (septal e′/s′)

Critical Care, 2017
Background Left ventricular diastolic dysfunction is associated with mortality outcomes in severe sepsis and septic shock. There are ongoing issues with diagnosing diastolic dysfunction in this cohort, partly owing to the poor applicability of ...
David J. Clancy, Michel Slama, Stephen Huang, Timothy Scully, Anthony S. McLean, Sam R. Orde   +5 more
doaj   +1 more source

Use, timing and factors associated with tracheal intubation in septic shock: a prospective multicentric observational study

Annals of Intensive Care, 2020
Background No recommendation exists about the timing and setting for tracheal intubation and mechanical ventilation in septic shock. Patients and methods This prospective multicenter observational study was conducted in 30 ICUs in France and Spain.
C. Darreau, F. Martino, M. Saint-Martin, S. Jacquier, J. F. Hamel, M. A. Nay, N. Terzi, G. Ledoux, F. Roche-Campo, L. Camous, F. Pene, T. Balzer, F. Bagate, J. Lorber, P. Bouju, C. Marois, R. Robert, S. Gaudry, M. Commereuc, M. Debarre, N. Chudeau, P. Labroca, K. Merouani, P. Y. Egreteau, V. Peigne, C. Bornstain, E. Lebas, F. Benezit, S. Vally, S. Lasocki, A. Robert, A. Delbove, N. Lerolle   +32 more
doaj   +1 more source

Predictive factors for severe long-term chronic kidney disease after acute kidney injury requiring renal replacement therapy in critically ill patients: an ancillary study of the ELVIS randomized controlled trial

Critical Care, 2022
Background Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is a serious complication in the ICU that results in increased mortality and risk of chronic kidney disease (CKD). Some studies suggest RRT modality may have an impact on long-
Edouard Soum, Jean-François Timsit, Stephane Ruckly, Didier Gruson, Emmanuel Canet, Kada Klouche, Laurent Argaud, Maïté Garrouste-Orgeas, Christophe Mariat, François Vincent, Sophie Cayot, Michael Darmon, Julien Bohé, Carole Schwebel, Lila Bouadma, Claire Dupuis, Bertrand Souweine, Alexandre Lautrette   +17 more
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source

The Effectiveness of Bevacizumab in COVID-19 Pneumonia Among Critically Ill Patients

Egyptian Journal of Critical Care Medicine, 2022
Background Bevacizumab, an antiangiogenic drug, is being evaluated for the management of novel coronavirus disease (COVID-19) pneumonia among critically ill patients.
Karthikkeyan Rajachandran, Giphy Susan Varghese, J. Vinoth Kumar, Santhosh Raja, S. K. Jagadish Chandran, M. Aruloli, A. Murali   +6 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The role of routine FIBERoptic bronchoscopy monitoring during percutaneous dilatational TRACHeostomy (FIBERTRACH): a study protocol for a randomized, controlled clinical trial

Trials, 2021
Background Tracheostomy is one of the most frequent techniques in intensive care units (ICU). Fiberoptic bronchoscopy (FB) is a safety measure when performing a percutaneous dilatational tracheostomy (PDT), but the controversy surrounding the routine use
José M. Añón, María Soledad Arellano, Manuel Pérez-Márquez, Claudia Díaz-Alvariño, José A. Márquez-Alonso, Jorge Rodríguez-Peláez, Kapil Nanwani-Nanwani, Ana Martín-Pellicer, Belén Civantos, Alba López-Fernández, Irene Seises, Jorge García-Nerín, Juan C. Figueira, Henar Casero, Javier Vejo, Alexander Agrifoglio, Lucía Cachafeiro, Mariana Díaz-Almirón, Jesús Villar   +18 more
doaj   +1 more source

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit

Open Forum Infectious Diseases, 2018
Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr, U. Jaschinski, X. Wittebole, T. Szakmany, J. Lipman, S. Ñamendys-Silva, I. Martín-Loeches, M. Leone, M. Lupu, J. Vincent   +9 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source