Results 61 to 70 of about 2,122,051 (402)
Cardiovascular Therapeutics, 2022 Reperfusion therapy, the standard treatment for acute myocardial infarction (MI), can trigger necrotic death of cardiomyocytes and provoke ischemia/reperfusion (I/R) injury.
Yi Ge +4 more
doaj +1 more source
Near-infrared spectroscopy after high-risk congenital heart surgery in the paediatric intensive care unit [PDF]
, 2011 Objective: To establish whether the use of near-infrared spectroscopy is potentially beneficial in high-risk cardiac infants in United Kingdom paediatric intensive care units. Design: A prospective observational pilot study.
Hovarth +5 more
core +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Trials, 2021 Background Tracheostomy is one of the most frequent techniques in intensive care units (ICU). Fiberoptic bronchoscopy (FB) is a safety measure when performing a percutaneous dilatational tracheostomy (PDT), but the controversy surrounding the routine use
José M. Añón +18 more
doaj +1 more source
Artificial intelligence in the intensive care unit
Critical Care, 2019 The use of artificial intelligence (AI) in healthcare is receiving increasing interest, driven by a surge in scientific research and funding. AI has shown ophthalmologist-level performance at detecting retinal pathology [1] and can provide individualised
C. Lovejoy, V. Buch, M. Maruthappu
semanticscholar +1 more source
The forgotten mothers of extremely preterm babies : A qualitative study [PDF]
, 2019 © 2019 The Authors. Journal of Clinical Nursing Published by John Wiley & Sons LtdAims and objectives: To explore the experiences of mothers of extremely prematurebabies during their Neonatal Intensive Care Unit stay and transition home.
Elliott, Doug +4 more
core +3 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit
Open Forum Infectious Diseases, 2018 Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr +9 more
semanticscholar +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Delirium in the intensive care unit [PDF]
Critical Care, 2008 Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the sickest intensive care unit (ICU) populations. Critically ill patients are subject to numerous risk factors for delirium.
E. Wesley Ely +3 more
openaire +3 more sources