Changing Place of Death in Children who died after discharge from Paediatric Intensive Care Units : a national, data linkage study [PDF]
Background: Although child mortality is decreasing, more than half of all deaths in childhood occur in children with a life-limiting condition whose death may be expected.
Bradford Health Authority and City of Bradford Metropolitan District Council+18 more
core +2 more sources
Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau+3 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Intensive care unit discharge to the ward with a tracheostomy cannula as a risk factor for mortality: A prospective, multicenter propensity analysis [PDF]
To analyze the impact of decannulation before intensive care unit discharge on ward survival in nonexperimental conditions. DESIGN: Prospective, observational survey.
Fernandez, R. (Rafael)+10 more
core
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Neonatal intensive care and its application in Malta [PDF]
The introduction of neonatal techniques has proved vital in the reduction of infant mortality rates. This article describes 4 important and basic techniques in neonatal intensive care; ventilation, nutrition, monitoring and cerebral assessment.
Azzopardi, Denis
core
Multi‐institutional study on image quality for a novel CBCT solution on O‐ring linac
Abstract Introduction This work presents a multi‐institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.
Luis Agulles‐Pedrós+11 more
wiley +1 more source
Near-infrared spectroscopy after high-risk congenital heart surgery in the paediatric intensive care unit [PDF]
Objective: To establish whether the use of near-infrared spectroscopy is potentially beneficial in high-risk cardiac infants in United Kingdom paediatric intensive care units. Design: A prospective observational pilot study.
Hovarth+5 more
core +1 more source
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard+7 more
wiley +1 more source
Impact of serum magnesium levels in critically ill elderly patients—A study in a rural teaching hospital [PDF]
Background/PurposeMagnesium deficiency has been a common, but easily ignored, electrolyte abnormality. Studies on magnesium deficiency are lacking in India, especially in a rural setting.
Agrawal, Sachin+3 more
core +1 more source