Results 31 to 40 of about 38,981 (201)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

JOSEPH BUTLER Y EL CONTEXTO DE LA CONCIENCIA UNA LECTURA DE LOS FIFTEEN SERMONS PREACHED AT THE ROLLS CHAPEL

open access: yesPraxis Filosófica, 2011
El artículo busca, a través de una exposición general de su obra de filosofíamoral, presentar la concepción de la conciencia moral desarrollada por JosephButler. Se busca así presentar el pensamiento de este autor a la comunidadfilosófica hispanoparlante,
Manfred Svensson
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Algunos efectos de la expansión monetaria en las tasas de interés del mercado de préstamos

open access: yesPensamiento Crítico, 2012
Este artículo señala que el empresario que prevé un alza de precios busca préstamos en el mercado dispuesto a pagar mayores intereses. El prestamista que prevé un alza de precios, solo otorga préstamos si el interés de mercado sube por encima del interés
Pablo Rivas Santos
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Juventud universitaria e interés por la política

open access: yesRevista Internacional de Pensamiento Político, 2022
La literatura académica entiende, de forma consensuada, que la participación política debe encontrarse en el centro de la democracia. Pero, en torno al significado del concepto en sí de participación política, aparecen disensos.
GLORIA MARTÍNEZ-COUSINOU   +2 more
doaj  

La motivación de los alumnos en la clase de lengua extranjera. Resultados de una investigación empírica en el contexto del uso de las tecnologías de comunicación e información

open access: yesPulso: Revista de Educación, 2009
Los resultados expuestos en este artículo se basan en una investigación sobre el tema software y uso de Internet en la clase de español: desarrollo de la motivación y la autoevaluación (Grünewald, 2006). El presente estudio tiene por objeto comprobar: a)
Andreas Grünewald
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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