Results 31 to 40 of about 39,465 (198)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Praxis Filosófica, 2011 El artículo busca, a través de una exposición general de su obra de filosofíamoral, presentar la concepción de la conciencia moral desarrollada por JosephButler. Se busca así presentar el pensamiento de este autor a la comunidadfilosófica hispanoparlante,
Manfred Svensson
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Algunos efectos de la expansión monetaria en las tasas de interés del mercado de préstamos
Pensamiento Crítico, 2012 Este artículo señala que el empresario que prevé un alza de precios busca préstamos en el mercado dispuesto a pagar mayores intereses. El prestamista que prevé un alza de precios, solo otorga préstamos si el interés de mercado sube por encima del interés
Pablo Rivas Santos
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Juventud universitaria e interés por la política
Revista Internacional de Pensamiento Político, 2022 La literatura académica entiende, de forma consensuada, que la participación política debe encontrarse en el centro de la democracia. Pero, en torno al significado del concepto en sí de participación política, aparecen disensos.
GLORIA MARTÍNEZ-COUSINOU +2 more
doaj
Pulso: Revista de Educación, 2009 Los resultados expuestos en este artículo se basan en una investigación sobre el tema software y uso de Internet en la clase de español: desarrollo de la motivación y la autoevaluación (Grünewald, 2006). El presente estudio tiene por objeto comprobar: a)
Andreas Grünewald
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source