Results 111 to 120 of about 8,082,089 (306)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Pragmatics & Interaction, Volume 1

, 2009
Talk-in-interaction: Multilingual perspectives offers original studies of interaction in a range of languages and language varieties, including Chinese, English, Japanese, Korean, Spanish, Swahili, Thai, and Vietnamese; monolingual and bilingual ...
Kasper, Gabriele, Nguyen, Hanh thi
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The influence of avatar generation and appearance on embodiment and user experience in virtual reality

Frontiers in Virtual Reality
Consumer-grade virtual reality (VR) now allows embodying full-body avatars to act within the virtual world. Although the effect of avatar appearance on embodiment has been investigated in several studies, the role of user involvement in the creation ...
Judith Hartfill, Frederico Bormann, Erik Wolf, Frank Steinicke   +3 more
doaj   +1 more source

Interactivity and thought [PDF]

, 2011
A shared tenet of embodied, embedded, situated and distributed cognition is that people make sense of things interactively. They run a simulation, they exchange words, often taking turns to change and steer the flow of interaction; they gesture, they handle or manipulate things, they write, sketch or model.
Kirsh, David, Goldin-Meadow, Susan, Clark, Herb, Rogers, Yvonne   +3 more
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Do you have AI dependency? The roles of academic self-efficacy, academic stress, and performance expectations on problematic AI usage behavior

International Journal of Educational Technology in Higher Education
Although previous studies have highlighted the problematic artificial intelligence (AI) usage behaviors in educational contexts, such as overreliance on AI, no study has explored the antecedents and potential consequences that contribute to this problem.
Shunan Zhang, Xiangying Zhao, Tong Zhou, Jang Hyun Kim   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Technology enhanced interaction framework

, 2013
This paper focuses on the development of a general interaction framework to help design technology to support communication between people and improve interactions between people, technology and objects, particularly in complex situations.
Wald, Mike, Gilbert, Lester, Angkananon, Kewalin   +2 more
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source