Results 91 to 100 of about 6,173,743 (316)

Anthropomorphic AI: a toolkit for authoring and interacting with intelligent virtual agents for extended reality

Frontiers in Virtual Reality
Intelligent Virtual Agents (IVAs), which embody an artificial intelligence (AI) in a humanoid representation, have enormous potential for immersive extended reality (XR) environments to enable natural and engaging human-AI interactions.
Ke Li, Fariba Mostajeran, Sebastian Rings, Julia Hertel, Susanne Schmidt, Michael Arz, Frank Steinicke   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Habituated interaction and social objects

, 2013
In this position paper we draw from critical approaches to the concept of habit from cultural theory to argue that considering the sociality of everyday objects might be productive for understanding and designing for habituated interaction within the ...
Brereton, Margot, Robertson, T, Nansen, B, Durick, JI, Robertson, Toni, Brereton, M, Durick, J, Vetere, Frank, Vetere, F, Nansen, Bjorn, Durick, Jeannette   +10 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Computations and Interaction [PDF]

, 2011
We enhance the notion of a computation of the classical theory of computing with the notion of interaction. In this way, we enhance a Turing machine as a model of computation to a Reactive Turing Machine that is an abstract model of a computer as it is used nowadays, always interacting with the user and the world.
J.C.M. Baeten (Jos), S.P. Luttik (Bas), P.J.A. van Tilburg (Paul)   +2 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

To Interact or not to Interact: Pros and Cons of Including Interactions in Linear Regression Models

Behavior Research Methods
Interaction effects are very common in the psychological literature. However, interaction effectsare typically very small and often fail to replicate. In this study, we conducted a simulationcomparing the generalizability and estimability of two linear regression models: one correctlyspecified to account for interaction effects and one misspecified ...
Aljoscha Rimpler, Henk A.L. Kiers, Don van Ravenzwaaij   +2 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The art of interaction [PDF]

Digital Creativity, 2010
Interactive art has become much more common as a result of the many ways in which the computer and the Internet have facilitated it. Issues relating to Human-Computer Interaction are as important to interactive art making as issues relating to the colours of paint are to painting. It is not that HCI and art necessarily share goals. It is just that much
openaire   +3 more sources