Results 131 to 140 of about 8,082,089 (306)

Concept-Driven Interaction Design Research

open access: yes, 2010
In this article, we explore a concept-driven approach to interaction design research with a specific focus on theoretical advancements. We introduce this approach as a complementary approach to more traditional, and well-known, user-centered interaction ...
Mikael Wiberg   +3 more
core   +1 more source

Worlds apart? Investigating acceptance and usage demands of carbon-based cosmetics and clothing across European countries

open access: yesEnergy, Sustainability and Society
Background Global warming and the increasing risk of natural disasters force us all to act. As the reduction of carbon dioxide (CO2) emissions has been proven effective but insufficient on its own, Carbon Capture and Utilization (CCU) technologies ...
Wiktoria Wilkowska   +2 more
doaj   +1 more source

Exploring a GPT-based large language model for variable autonomy in a VR-based human-robot teaming simulation

open access: yesFrontiers in Robotics and AI
In a rapidly evolving digital landscape autonomous tools and robots are becoming commonplace. Recognizing the significance of this development, this paper explores the integration of Large Language Models (LLMs) like Generative pre-trained transformer ...
Younes Lakhnati   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Patterns of interactions: user behaviour in response to search results [PDF]

open access: yes, 2002
This paper presents patterns of users’ interaction when working with digital libraries. It focuses on strategies developed and applied by users over time to achieve their goals.
Blandford, A, Stelmaszewska, H
core  

Decoding drug resistance: the role of m6A modification in cisplatin efficacy

open access: yesEuropean Journal of Medical Research
Cisplatin is one of the most widely used chemotherapeutic drugs in treating malignant tumors. However, its clinical efficacy is severely compromised by the emergence of drug resistance.
Zile Zhang   +8 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

ScaleMamba-YOLO: a multi-scale MambaYOLO for medical object detection

open access: yesScientific Reports
The efficacy of automated lesion detection in clinical settings is often hampered by two primary factors: the vast range of pathological scales and the presence of non-target anatomical interference.
Xiao Qin   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The Effects of Wake Dynamics and Trailing Edge Flap on Wind Turbine Blade [PDF]

open access: yes, 2014
In the present study, we considered the bladewake interaction (BWI) and the TEF span length, index angle on a turbine blade. The aerodynamic loads and the stresses on the blade were studied. The wake dynamic theory, BEM, and the ANSYS-FORTRAN APDL method
Wang, Yi-Ren; Chiu, Chien-Chih   +2 more
core  

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