Results 191 to 200 of about 16,557,675 (399)

Beyond contacts: The important role of the support region in protein complex assembly. [PDF]

Protein Sci
Miclot T, Timr S.
europepmc   +1 more source

Young Children and Voice Search: What We Know From Human-Computer Interaction Research [PDF]

, 2019
Silvia B. Lovato, Anne Marie Piper
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Impact of genotype × environment interaction and selection history on genomic prediction in maize (Zea mays L.) [PDF]

Martin Costa, James B. Holland, Natalia de León, Shawn M. Kaeppler   +3 more
openalex   +1 more source

Origin of large thermal effect in the Casimir interaction between two graphene sheets [PDF]

, 2015
G. L. Klimchitskaya, V. M. Mostepanenko
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Parallels between the chloro and methoxy groups for potency optimization. [PDF]

RSC Med Chem
Chiodi D, Ishihara Y.
europepmc   +1 more source

A Planar Diagram Theory for Strong Interactions

, 1974
G. Hooft
semanticscholar   +1 more source

Revealing noncovalent interactions.

Journal of the American Chemical Society, 2010
E. Johnson, Shahar Keinan, P. Mori-Sánchez, J. Contreras‐García, A. Cohen, Weitao Yang   +5 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source