Results 281 to 290 of about 16,557,675 (399)

IID 2025: Physical protein interaction data with detection types, co-purified protein sets, molecular docking, and immune cell networks. [PDF]

Nucleic Acids Res
Kotlyar M, Pastrello C, Abovsky M, Mizeranschi A, Keating A, Cameron LC, Chandran V, Jurisica I.   +7 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Extra-role interpersonal interactions in Chinese organizational contexts: construct, measurement, and validity. [PDF]

Front Psychol
Liu X, Zhao X, Bai L, Qian X.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Correction: A tripartite bacterial-fungal-plant symbiosis in the mycorrhiza-shaped microbiome drives plant growth and mycorrhization

Microbiome
Changfeng Zhang, Marcel G. A. van der Heijden, Bethany K. Dodds, Thi Bich Nguyen, Jelle Spooren, Alain Valzano‑Held, Marco Cosme, Roeland L. Berendsen   +7 more
doaj   +1 more source

On the same side: VISTA and its ligands interact in cis on the cell surface. [PDF]

Protein Sci
Smorodinsky-Atias K, Wiseglass G, Artyukhova A, Salem M, Kashani M, Boni N, Levy R, Rubinstein R.   +7 more
europepmc   +1 more source

Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity

, 2019
Arvind Negi, C Reilly, Dilip V. Jarikote, Jian Zhou, Paul V. Murphy   +4 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Unifying microorganisms and macrograzers in intertidal rocky shore ecological networks. [PDF]

Ecology
Arboleda-Baena C, Pareja CB, Poblete J, Berlow EL, Sarmento H, Logares R, De la Iglesia R, Navarrete SA.   +7 more
europepmc   +1 more source