Results 61 to 70 of about 9,657,547 (300)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Seed tuber imprinting shapes the next-generation potato microbiome

Environmental Microbiome
Background Potato seed tubers are colonized and inhabited by soil-borne microbes, that can affect the performance of the emerging daughter plant in the next season.
Yang Song, Jelle Spooren, Casper D. Jongekrijg, Ellen J. H. H. Manders, Ronnie de Jonge, Corné M. J. Pieterse, Peter A. H. M. Bakker, Roeland L. Berendsen   +7 more
doaj   +1 more source

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum

mBio, 2017
Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gene contains a conserved intron which has been implicated in previous studies in both activation and ...
Jessica M. Bryant, Clément Regnault, Christine Scheidig-Benatar, Sebastian Baumgarten, Julien Guizetti, Artur Scherf   +5 more
doaj   +1 more source

A re‐innervated in vitro skin model of non‐histaminergic itch and skin neurogenic inflammation: PAR2‐, TRPV1‐ and TRPA1‐agonist induced functionality

Skin Health and Disease, 2021
Background Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them and signal transduction are only partially elucidated in physiological/pathological conditions, especially in pruritus.
N. Lebonvallet, J. W. Fluhr, C. Le Gall‐Ianotto, R. Leschiera, M. Talagas, A. Reux, A. Bataille, C. Brun, T. Oddos, J.‐P. Pennec, J.‐L. Carré, L. Misery   +11 more
doaj   +1 more source

Interaction hierarchy

Physics Letters B, 1994
We analyse a new class of statistical systems, which simulate different systems of random surfaces on a lattice. Geometrical hierarchy of the energy functionals on which these theories are based produces corresponding hierarchy of the surface dynamics and of the phase transitions.
Savvidy, G. K., Savvidy, K. G.
openaire   +2 more sources

Protoplanet Magnetosphere Interactions

, 2006
In this paper, we study a simple model of an orbiting protoplanet in a central magnetospheric cavity, the entry into such a cavity having been proposed as a mechanism for halting inward orbital migration.
Armitage, Cameron, Chandrasekhar, Frieman, Ghosh, Goldreich, Hoyle, J. C. B. Papaloizou, Johns-Krull, Joss, Lin, Lynden-Bell, Marcy, Masset, Matt, Mayor, Muzerolle, Ménard, Nelson, Papaloizou, Papaloizou, Pringle, Romanova, Romanova, Ruffert, Safier, Tremaine, Zhang   +27 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Next-Generation Sequencing for Binary Protein-Protein Interactions

Frontiers in Genetics, 2015
The yeast two-hybrid (Y2H) system exploits host cell genetics in order to display binary protein-protein interactions (PPIs) via defined and selectable phenotypes.
Bernhard eSuter, Xinmin eZhang, Gustavo ePesce, Andrew eMendelsohn, Andrew eMendelsohn, Savithramma eDinesh-Kumar, Jian-Hua eMao   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

"Secret" neutrino interactions [PDF]

, 1999
We review the information about a potentially strong non-standard four-neutrino interaction that can be obtained from available experimental data. By using LEP results and nucleosynthesis data we find that a contact four-fermion neutrino interaction that
Bilenky, Mikhail, Santamaria, Arcadi
core   +1 more source