Results 71 to 80 of about 5,221,406 (297)

On Interaction Quality in Human-Robot Interaction

open access: yesProceedings of the 9th International Conference on Agents and Artificial Intelligence, 2017
In many complex robotics systems, interaction takes place in all directions between human, robot, and environment. Performance of such a system depends on this interaction, and a proper evaluation of a system must build on a proper modeling of interaction, a relevant set of performance metrics, and a methodology to combine metrics into a single ...
Suna Bensch   +2 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Replication Data for: Do Safety Expectations Affect the Location Strategies of Large Service Delivery INGOs?

open access: yes, 2023
Large service-delivery international nongovernmental organizations (INGOs) help shape the lives of millions worldwide, contributing significantly to the betterment of global health, development, education, and more.
Interactions, International
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Replication Data for: Direction Augmentation in the Evaluation of Armed Conflict Predictions

open access: yes, 2023
In many forecasting settings, there is a specific interest in predicting the sign of an outcome variable correctly in addition to its magnitude. For instance, when forecasting armed conflicts, positive and negative logchanges in monthly fatalities ...
Interactions, International
core   +1 more source

Next-Generation Sequencing for Binary Protein-Protein Interactions

open access: yesFrontiers in Genetics, 2015
The yeast two-hybrid (Y2H) system exploits host cell genetics in order to display binary protein-protein interactions (PPIs) via defined and selectable phenotypes.
Bernhard eSuter   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Cropping practices manipulate abundance patterns of root and soil microbiome members paving the way to smart farming

open access: yesMicrobiome, 2018
Background Harnessing beneficial microbes presents a promising strategy to optimize plant growth and agricultural sustainability. Little is known to which extent and how specifically soil and plant microbiomes can be manipulated through different ...
Kyle Hartman   +5 more
doaj   +1 more source

A re‐innervated in vitro skin model of non‐histaminergic itch and skin neurogenic inflammation: PAR2‐, TRPV1‐ and TRPA1‐agonist induced functionality

open access: yesSkin Health and Disease, 2021
Background Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them and signal transduction are only partially elucidated in physiological/pathological conditions, especially in pruritus.
N. Lebonvallet   +11 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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