Results 91 to 100 of about 270,110 (298)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Scrutinizing Metadiscourse Functions in Indonesian EFL Students: A Case Study on the Classroom Written and Spoken Discourses [PDF]
Mextesol Journal, 2021 Many scholars have investigated metadiscourse use in academic settings, but they have mostly explored written data, such as academic essays and research articles. However, spoken discourses like student presentations are rarely explored. Extant studies
Fatimatuz Zahro +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
gamma-sky.net: Portal to the Gamma-Ray Sky
, 2017 Gamma-sky.net is a novel interactive website designed for exploring the gamma-ray sky. The Map View portion of the site is powered by the Aladin Lite sky atlas, providing a scalable survey image tesselated onto a three-dimensional sphere.
Deil, Christoph +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
TOPCAT: Desktop Exploration of Tabular Data for Astronomy and Beyond
, 2017 TOPCAT, the Tool for OPerations on Catalogues And Tables, is an interactive desktop application for retrieval, analysis and manipulation of tabular data, offering a powerful and flexible range of interactive visualization options amongst other features ...
Taylor, Mark
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Journal of English Education and Teaching, 2019 This research is aimed to find metadiscourse form and metadiscourse category which are dominantly used in the undergraduate thesis introduction written by English Department students of Bengkulu University.
Putri Agustinos +2 more
doaj +1 more source
Speech markers in social interaction
, 1979 Originally published in 1979, this book presents an interdisciplinary study of the role of social markers in speech. Each chapter explores the nature and functioning of speech markers from a different social, biological or psychological perspective, and the volume offers a systematic survey of facts and ideas concerning the remarkable wealth of ...
Giles, Howard +2 more
openaire +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source