Results 111 to 120 of about 70,986 (299)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Disciplinary variation in argumentative essays: Mapping metadiscourse patterns in undergraduate writing

Ampersand
Academic writing is not only content-oriented but also involves various rhetorical strategies that enable authors to project themselves into the text.
Attapol Khamkhien
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

From Codes to Patterns: Designing Interactive Decoration for Tableware [PDF]

, 2013
We explore the idea of making aesthetic decorative patterns that contain multiple visual codes. We chart an iterative collaboration with ceramic designers and a restaurant to refine a recognition technology to work reliably on ceramics, produce a pattern
Quinn, Anthony, Benford, Steve, Koleva, Boriana, Baurley, Sharon, Mortier, Richard, Ali, Shakir, Thorn, Emily Clare, Pridmore, Tony   +7 more
core  

Metadiscourse Markers in Pure Mathematics Textbooks

, 2017
The aim of this study was to investigate the use of metadiscourse markers in Mathematics textbooks. To achieve this objective, four chapters of A First Course in Abstract Algebra were selected for data collection.
Amir Mohammadian, Hassan Banaruee, Esmail Zare-Behtash   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

L2 Learners’ Use of Metadiscourse Markers in Online Discussion Forums [PDF]

Issues in Language Teaching, 2012
This study aimed to investigate the use of interactional metadiscourse markers in 168 comments made by 28 university students of engineering via an educational forum held as part of a general English course.
zis tajeddin, minoo alemi
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Constructing Gender through Meta discourse: A Corpus-Based Inter-Disciplinary Study of Research Dissertations of Pakistani M. Phil Graduates

Corporum, 2023
Viewed in the social context, academic writing is considered a site where both writers and readers are engaged in an interactive mode of presentation and evaluation of information. Male and female writers may differently exemplify the interactive mode of
Musarrat Azher, Humaira Jahangir, Rashid Mahmood   +2 more
doaj  

Bueno: A Spanish Interactive Discourse Marker

Annual Meeting of the Berkeley Linguistics Society, 1998
Proceedings of the Twenty-Fourth Annual Meeting of the Berkeley Linguistics Society: General Session and Parasession on Phonetics and Phonological Universals (1998)
openaire   +2 more sources