Results 201 to 210 of about 70,986 (299)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

A CONTRASTIVE ANALYSIS OF INTERACTIVE MARKERS IN B1/B2 CEFR LEVEL IN ESSAYS

open access: yes
[ES] En este TFM se realiza un estudio y análisis contrastivo de los marcadores interactivos en un corpus de ensayos de nivel B1 y B2. El objetivo principal de este proyecto es identificar las diferencias en el uso de los marcadores interactivos en ...
Torres Vega, Ana
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Mapping Immunity With Cutting-Edge Spatial Biology and Tissue Cytometry Innovations. [PDF]

open access: yesMedComm (2020)
Cárdenas-Piedra L   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The MARC SE-Africa dashboard: Joining forces to counteract emerging antimalarial resistance in South and East Africa. [PDF]

open access: yesPLOS Digit Health
van Wyk S   +22 more
europepmc   +1 more source

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