Results 61 to 70 of about 70,986 (299)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Disrupted network interactions serve as a neural marker of dyslexia
AbstractDyslexia, a frequent learning disorder, is characterized by severe impairments in reading and writing and hypoactivation in reading regions in the left hemisphere. Despite decades of research, it remains unclear to date if observed behavioural deficits are caused by aberrant network interactions during reading and whether differences in ...
Sabrina Turker +3 more
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Imperceptible AR Markers for Near-Screen Mobile Interaction [PDF]
Owing to the pervasive use of displays and smartphones, mobile interactions with display screens have gained attention within the advertising and gaming industries as well as in human-computer interaction research. Communication through QR code-like markers and localization via AR markers are common examples of such interactions. However, these visible
Akira Matsumoto +4 more
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
O objetivo deste trabalho é focalizar, numa perspectiva textual-interativa, como o gênero discursivo carta do leitor foi se constituindo e se modificando a partir das necessidades interacionais, isto é, o dialogismo estabelecido entre o escrevente e seu ...
Maria Lúcia da Cunha Victório de Oliveira Andrade
doaj
There is lack of studies on the use of metadiscourse markers; especially amongst international students studying in Malaysia and Malaysia are receiving scores of international students particularly from the Middle East annually.
Khairul Zakaria Muhamad +1 more
doaj +1 more source
Since the discovery of the mirror neuron system in the 1990s, little, if any, research has been devoted to the study of interactive motor tasks (Goldman, 2012).
Edson eFilho +7 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Gender-based Study of Interactive and Interactional Metadiscourse Markers in Conclusion Sections of English Master Theses [PDF]
The aim of this study is to seek two types of interpersonal model of Hyland (2005) used in conclusion sections of 30 Master Theses of English Teaching, English Literature, and English Translation written by male and female graduate students.
Baharlooei, Roya +5 more
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