Results 181 to 190 of about 1,031,896 (310)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Blended learning environment versus interactive lecture in life rules; applied ethics course for medical sciences digital natives: An evaluation based on Kirkpatrick's model. [PDF]

J Educ Health Promot
Bahrami M, Seidi M, Rashti R, Babaei S.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Online Communication Attitudes and Video Game Co-Play in Older Adults: Cross-Sectional Mediation Study. [PDF]

JMIR Aging
Tseng JT.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Interactive media for childhood obesity prevention. [PDF]

Health Commun, 2010
Lu AS, Baranowski J, Cullen KW, Jago R, Thompson D, Baranowski T.   +5 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Interactive Media-Based Approach for an Exception From Informed Consent Trial Involving Patients With Trauma.

JAMA Surg
Stephens SW, Carroll-Ledbetter C, Duckert S, Coffman T, Nelson M, Brown KN, Rodgers J, Griffin RL, Suen A, Casey J, Sloan SR, Goldstein B, McClintock AJ, Goldkind SF, Gelinas L, Higley AE, Joseph BA, Holcomb JB, Jansen JO, TAP Study Group.   +19 more
europepmc   +1 more source

Digital art as a novel medium for health communication: enabling interactive interventions and reconstructing health experiences in public health. [PDF]

Front Public Health
Guo RL, Sun Y.
europepmc   +1 more source