Results 71 to 80 of about 203,102 (284)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Learning interaction patterns using diagrams varying in level and type of interactivity [PDF]

open access: yes, 2005
An experiment was conducted to investigate the differences between learners when using computer based learning environments (CBLEs) that incorporated different levels of interactivity in diagrams.
du Boulay, Benedict   +2 more
core   +1 more source

Optimized Data Representation for Interactive Multiview Navigation [PDF]

open access: yes, 2017
In contrary to traditional media streaming services where a unique media content is delivered to different users, interactive multiview navigation applications enable users to choose their own viewpoints and freely navigate in a 3-D scene.
Frossard, Pascal   +2 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Museus, ciência e educação: novos desafios Museums, science, and education: new challenges

open access: yesHistória, Ciências, Saúde: Manguinhos, 2005
Este artigo discute a conformação do papel social dos museus de ciência pelo fazer científico e tecnológico, pelas demandas da sociedade e pelas questões educacionais, sobretudo na negociação com seus públicos.
Maria Esther Valente   +2 more
doaj   +1 more source

Learning and interactivity in solving a transformation problem [PDF]

open access: yes, 2015
Outside the psychologist's laboratory, thinking proceeds on the basis of a great deal of interaction with artefacts that are recruited to augment problem-solving skills. The role of interactivity in problem solving was investigated using a river-crossing
Guthrie, Lisa   +3 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Information and the Transformation of Sociology: Interactivity and Social Media Monitoring

open access: yestripleC: Communication, Capitalism & Critique, 2012
This paper explores some key ways in which the scale and form of information today challenges sociology’s methods and practice. Information has shaped sociology in two key ways.
Hugh Mackay
doaj   +1 more source

Science and Technology in Media [PDF]

open access: yes, 2015
Tato práce se zabývá vlivem médií, především nových médií, na oblast vědy a techniky. Definuje základní mediální pojmy a upozorňuje na to, že média mohou být výborným prostředkem k propagaci vědy a techniky, ale mají také obrovskou moc a mohou zkreslovat
Gellnerová, Zuzana
core  

Transitioning Between Audience and Performer: Co-Designing Interactive Music Performances with Children

open access: yes, 2017
Live interactions have the potential to meaningfully engage audiences during musical performances, and modern technologies promise unique ways to facilitate these interactions.
Fails Jerry Alan   +4 more
core   +1 more source

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