Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source
Proximity labeling strategies in Caenorhabditis elegans: a comprehensive review. [PDF]
Balasubramaniam B, van der Hoeven R.
europepmc +1 more source
This integrated systems biology study of 2847 exposure‐related genes identifies a conserved 647‐gene core and CYP1B1 hub across cigarette smoke, ozone, and PM2.5. Three key pathways converge, enabling computational repurposing of 15 drug candidates (e.g., NRF2 activators) for environmentally induced COPD.
Fakher Rahim +2 more
wiley +1 more source
A Biochemical Analysis of LINC00896 RNA in Cortex Neuronal Cells and Its Possible Connection to the Development of Autism. [PDF]
Hellmann Whitaker RA +8 more
europepmc +1 more source
Chemical biology tools for studying histone post-translational modifications. [PDF]
Douglas CJ, Seath CP.
europepmc +1 more source
Structural variations in evolutionary novel genomic regions: new insights into neurodevelopmental disorders by long-read DNA Sequencing. [PDF]
Rincic M +7 more
europepmc +1 more source
Co-Immunoprecipitation-Coupled Mass Spectrometry Analysis of Zyxin's Interactome and Phosphosites in Early <i>Xenopus laevis</i> Development. [PDF]
Parshina EA +3 more
europepmc +1 more source
Myoferlin is a component of late-stage vRNP trafficking vesicles for enveloped RNA viruses. [PDF]
Bonazza S +11 more
europepmc +1 more source
Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition. [PDF]
Sottnik JL +15 more
europepmc +1 more source

