Results 291 to 300 of about 63,382 (353)

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou   +10 more
wiley   +1 more source

Precision environmental medicine: Integrated multi‐exposure transcriptomics for shared molecular networks in COPD pathogenesis in response to environmental exposure

open access: yesPrecision Medical Sciences, Volume 15, Issue 2, Page 147-159, June 2026.
This integrated systems biology study of 2847 exposure‐related genes identifies a conserved 647‐gene core and CYP1B1 hub across cigarette smoke, ozone, and PM2.5. Three key pathways converge, enabling computational repurposing of 15 drug candidates (e.g., NRF2 activators) for environmentally induced COPD.
Fakher Rahim   +2 more
wiley   +1 more source

A Biochemical Analysis of LINC00896 RNA in Cortex Neuronal Cells and Its Possible Connection to the Development of Autism. [PDF]

open access: yesJ Nucleic Acids
Hellmann Whitaker RA   +8 more
europepmc   +1 more source

Myoferlin is a component of late-stage vRNP trafficking vesicles for enveloped RNA viruses. [PDF]

open access: yesNat Commun
Bonazza S   +11 more
europepmc   +1 more source

Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition. [PDF]

open access: yesCancer Res
Sottnik JL   +15 more
europepmc   +1 more source

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