Results 181 to 190 of about 2,590,463 (283)

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

First-in-human testing of a mutant KRAS vaccine for pancreatic cancer interception in high-risk cohorts. [PDF]

Cancer Discov
Haldar SD, Huff AL, Wang HH, Zhu Z, Berg M, Lu J, Sun N, Abou Diwan E, Sinan H, Thoburn CJ, Guo MZ, Yoshida T, Chu LC, Ferguson AK, Sidiropoulos DN, Kagohara LT, Ho WJ, Bever KM, Baretti M, Yarchoan M, Laheru DA, Nauroth JM, Thomas AM, Wang H, Azad NS, Goggins MG, Jaffee EM, Zaidi N.   +27 more
europepmc   +1 more source

Synergistic Integration of Fe–N4 Single‐Atom Sites and Directionally Aligned Electrode Architecture for High‐Performance Lithium–Sulfur Batteries

Advanced Science, EarlyView.
A directionally ice‐templated sulfur cathode integrated with atomically dispersed Fe–N4 catalytic sites is developed for high‐performance lithium–sulfur batteries. The structure–catalysis synergy accelerates Li+ transport and polysulfide conversion, leading to high sulfur utilization and stable long‐term cycling performance.
Lin Shen, Yijia Zou, Yuming Wang, Erya Gao, Christopher S. Allen, Tianyi Zhang, Stephen J. Skinner, Nigel P. Brandon, Chun Huang   +8 more
wiley   +1 more source

Earlier Prostatic Artery Embolization for Progressive Benign Prostatic Hyperplasia: A Biological Rationale and Hypothesis for Disease Interception. [PDF]

Cureus
Sadowski J.
europepmc   +1 more source

When Mechanics Rewrites Chemistry: Divergent Pathways of Hardening and Softening in High Strength Al‐Alloys

Advanced Science, EarlyView.
Mechanics reshapes chemistry: plastic flow actively governs two divergent, atomic‐scale mechanochemical pathways that tailor strain localization and ductility in high‐strength 7xxx Al alloys. Rather than relying on static structures, deformation dynamically reinforces the solution‐treated state via clustering, yet destabilizes the peak‐aged condition ...
Huan Zhao, Linze Li, Shaolou Wei, Jueyi Qi, Jiewen Xiao, Degang Xie, Xie Zhang, Gang Liu, Dierk Raabe, Jun Sun   +9 more
wiley   +1 more source

A multifunctional Janus-inspired therapeutic patch enabling intraoperative control of tumor dissemination and unidirectional drug delivery. [PDF]

Mater Today Bio
Pan X, Wang X, Dang Q, Chen L, Wang G, Wang X, Xi S, Zhang H, Fang X.   +8 more
europepmc   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Leveraging Microbes for Sustainable Development Goal 14 Progress. [PDF]

Environ Microbiol Rep
Aurora R, Balmonte JP.
europepmc   +1 more source

Field experiments on interception loss Sugi needles- Preliminary report-

The Japanese Forest Society Congress, 2013
iwaya, ayako, Kaneko, Tomonori, Noguchi, Shoji   +2 more
openaire   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source