Results 91 to 100 of about 48,889 (290)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Calculation Methods and Techinques Used for Statistical Analysis Of Results Indicators [PDF]
Revista Română de Statistică, 2013 The objective of this work is to present the role of statistical methods in facilitating managerial decisions on the combination of production factors, taking account of the limited character of them, but the two aspects of economic activity: one ...
Florina Roman Stan
doaj
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Switching to Biosimilars in Inflammatory Rheumatic Conditions: Current Knowledge
European Medical Journal Rheumatology, 2018 Biosimilars are more affordable versions of previously approved biopharmaceuticals that are designed to reduce healthcare expenditure and increase patient access to this therapeutic class. To achieve their economic potential, many European countries have
Filipe C. Araújo +2 more
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Indian Journal of OphthalmologyThis study aimed to assess the interchangeability of pachymetry measurements obtained by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in children with congenital corneal opacity (CCO).
Sonam Yangzes +6 more
doaj +1 more source
SMS power and grounding. CEI part 1: Detail specification, type 1 data [PDF]
This specification establishes the requirements for performance, design, test, and qualification of the SMS total power and grounding system. This is defined as designing a new PDU to be useable for SMS adding FBCS and modifying and adding to the OAS ...
core +1 more source
First-Order Decomposition Trees [PDF]
, 2013 Lifting attempts to speed up probabilistic inference by exploiting symmetries in the model. Exact lifted inference methods, like their propositional counterparts, work by recursively decomposing the model and the problem. In the propositional case, there
Blockeel, Hendrik +2 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Focus on biosimilar etanercept – bioequivalence and interchangeability
Biologics: Targets & Therapy, 2018 Fabrizio Cantini,1 Maurizio Benucci2 1Department of Rheumatology, Hospital of Prato, Prato, Italy; 2Rheumatology Unit, Hospital S. Giovanni di Dio, Florence, Italy Background: The recent approval of reference etanercept (re-ETN) biosimilars SB4, GP2015 ...
Cantini F, Benucci M
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