Results 101 to 110 of about 48,889 (290)

"Repeated Games with Correlated Private Monitoring and Secret Price Cuts" [PDF]

open access: yes
This paper investigates general two-player infinitely repeated games where the discount factor is less than but close to unity. We assume that monitoring is imperfect and private, and players' private signals are correlated through the unobservable macro
Hitoshi Matsushima
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Actual questions of clinical pharmacology by amlodipine: should we prefer the original or a generic drug?

open access: yesКардиоСоматика, 2016
Selection of amlodipine (tablets) as a drug based on three basic criteria: clinical efficacy, safety / tolerability and quality is discussed below. The article deals with the successive stages of clinical pharmacology and pharmacotherapy from amlodipine ...
A. S Dukhanin
doaj  

Synonymic Representation of “Islamic World” in American Mass Media [PDF]

open access: yes, 2011
У статті представлено аналіз синонімічного ряду «Ісламської картини світу» у сучасній американській ...
Семенюк, І. С.   +1 more
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Switching from Reference to Biosimilar Products: An Overview of the European Approach and Real-World Experience So Far

open access: yesEuropean Medical Journal, 2018
Switching patients from a reference to a biosimilar product has become a primary topic of interest, with different approaches being undertaken by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
Anna La Noce, Marcin Ernst
doaj  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Technical report analysis and design: Study of solid rocket motors for a space shuttle booster, volume 2, book 1, supplement 1 [PDF]

open access: yes
An analysis and design effort was conducted as part of the study of solid rocket motor for a space shuttle booster. The 156-inch-diameter, parallel burn solid rocket motor was selected as its baseline because it is transportable and is the most cost ...

core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Experimental Evaluation of Branching Schemes for the CSP

open access: yes, 2010
The search strategy of a CP solver is determined by the variable and value ordering heuristics it employs and by the branching scheme it follows. Although the effects of variable and value ordering heuristics on search effort have been widely studied ...
Balafoutis, Thanasis   +2 more
core  

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