Results 21 to 30 of about 48,481 (274)
Generalizing Consistency and other Constraint Properties to Quantified Constraints [PDF]
Quantified constraints and Quantified Boolean Formulae are typically much more difficult to reason with than classical constraints, because quantifier alternation makes the usual notion of solution inappropriate.
Bordeaux, Lucas +2 more
core +2 more sources
Introduction: Biological products, including infliximab (INF), are a therapeutic option for various medical conditions. In the Peruvian Social Security (EsSalud), infliximab is approved for the treatment of rheumatoid arthritis, psoriasis, psoriatic ...
Edward Mezones-Holguin +8 more
doaj +1 more source
Hexavalent (HV) vaccination is a priority for newborn protection and in Italy is included in the National Immunization Plan with a three doses cycle at 61, 121 and 301 days of age.
Claudio Costantino +17 more
doaj +1 more source
The study objectives were to 1) explore the real-world experience of hospital pharmacists with the differences in effectiveness safety, and interchangeability between biosimilar medicines and their reference biological counterparts, 2) reveal pharmacist ...
Ali Azeez Al-Jumaili, Hiba Leith Fahmi
doaj +1 more source
Digital interchangeability design of aircraft control surfaces
With the gradual maturity and application of digital assembly technology,the interchangeability design adapting to digital quantity transfer is of significant practical significance for improving the efficiency of aircraft control surface design ...
LI Yunpeng, YAO Xionghua, GAO Shuai
doaj +1 more source
Symmetry Breaking Using Value Precedence
We present a comprehensive study of the use of value precedence constraints to break value symmetry. We first give a simple encoding of value precedence into ternary constraints that is both efficient and effective at breaking symmetry.
A. Adams +21 more
core +2 more sources
The high demand for and resulting financial success of biopharmaceutical products over the last three decades have seen the door open for close copies of these biological products, also known as biosimilars.
Eva Rahman Kabir +2 more
doaj +1 more source
On the Species Specificity of Acceptor RNA and Attachment Enzymes [PDF]
One of the steps in protein biosynthesis appears to be the attachment of each amino acid to a specific acceptor (SRNA) molecule. According to the adaptor hypothesis, each SRNA molecule would then fit to a specific complementary base sequence on a linear ...
Benzer, Seymour, Weisblum, Bernard
core +2 more sources
Successful implementation of interchange of biologic medications in chronic arthritis after information of costs to prescribers [PDF]
Aim: To evaluate the impact of prescription, cost, and switching policy on the rate of switching from reference products to biosimilars. Methods: Analysis of an administrative database for prescription in a rheumatology division.
Fernando Perez-Ruiz +8 more
doaj +1 more source
Biologics and biosimilars in musculoskeletal diseases: addressing regulatory inconsistencies and clinical uncertainty [PDF]
Biologics are complex protein-based medications derived from living organisms, used primarily to treat immune-related diseases. Unlike small-molecule drugs synthesized from chemicals, biologics are produced using advanced biotechnology, making their ...
Lauren N. McGrath +2 more
doaj +1 more source

