Results 41 to 50 of about 258,364 (276)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Autoimmune disease and interconnections with vitamin D
Endocrine Connections, 2022 Vitamin D has well-documented effects on calcium homeostasis and bone metabolism but recent studies suggest a much broader role for this secosteroid in human health.
Jane Fletcher +7 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Interconnections between Inflammageing and Immunosenescence during Ageing
Cells, 2022 Acute inflammation is a physiological response to injury or infection, with a cascade of steps that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal wounds.
Thibault Teissier +2 more
doaj +1 more source
Adaptive optical networks using photorefractive crystals [PDF]
, 1988 The capabilities of photorefractive crystals as media for holographic interconnections in neural networks are examined. Limitations on the density of interconnections and the number of holographic associations which can be stored in photorefractive ...
Brady, David +2 more
core
Advanced Exergy Analysis in the Dynamic Framework for Assessing Building Thermal Systems [PDF]
, 2019 This work applies the Dynamic Advanced Exergy Analysis (DAEA) to a heating and domestic hot water (DHW) facility supplied by a Stirling engine and a condensing boiler. For the first time, an advanced exergy analysis using dynamic conditions is applied to
Picallo-Perez, Ana +3 more
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Dangerous Liaisons: Relationships between design, craft and art [PDF]
, 2004 The introductory essay [co-authored] examines the background and current interconnections between design, craft and the fine arts. This Special Issue was able to expand the debate by showing how attitudes to materials – from 19C sculpture to current ...
Lees-Maffei, Grace, Sandino, Linda
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
CSEE Journal of Power and Energy Systems, 2018 Multinational power grid interconnections play a critical part in supporting the vision of global energy internet. During the early stages of the Global Energy Internet, the value proposition of multinational interconnections should be carefully ...
Xiaojun Wang +4 more
doaj +1 more source