Results 31 to 40 of about 553,337 (279)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Factors Shaping the Future of Leasing in Poland. The Role of External Shocks, Regulations, and Emerging Technologies

open access: yesInternational Journal of Management and Economics
This study aims to identify and evaluate the key trends in the leasing sector in Poland from the perspective of both the present situation and the coming years.
Radło Mariusz-Jan   +3 more
doaj   +1 more source

Fickle Judgments in Moral Dilemmas: Time Pressure and Utilitarian Judgments in an Interdependent Culture

open access: yesFrontiers in Psychology, 2022
In the trolley problem, a well-known moral dilemma, the intuitive process is believed to increase deontological judgments, while deliberative reasoning is thought to promote utilitarian decisions.
Hirofumi Hashimoto   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Leaders in Interdependent Contexts Suppress Nonverbal Assertiveness: A Multilevel Analysis of Japanese University Club Leaders' and Members' Rank Signaling

open access: yesFrontiers in Psychology, 2018
Previous research has shown that leadership is signaled through nonverbal assertiveness. However, those studies have been mostly conducted in individualistic cultural contexts, such as in the U.S.
Atsuki Ito   +2 more
doaj   +1 more source

Creating conditions for cooperative learning: Basic elements [PDF]

open access: yesZbornik Instituta za pedagoška istraživanja, 2003
Although a large number of research evidence speak out in favor of cooperative learning, its effectiveness in teaching does not depend only on teacher’s and students’ enthusiasm and willingness to work in such a manner. Creating cooperative situations in
Ševkušić-Mandić Slavica G.
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Partner choice increases observed reciprocity-based cooperation but decreases unobserved stake-based cooperation

open access: yesRoyal Society Open Science
According to current theory and experiments, cooperation is more likely to evolve when organisms can choose to replace uncooperative partners with cooperative ones. However, there is a downside to this partner choice: when partners can be easily replaced,
Pat Barclay
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

COUNTERFACTUAL DEPENDENCE, BOUNDARY AND RESOURCE DEPENDENCE

open access: yesJournal of International Studies
This study employs counterfactual dependence to explore boundary interactions in resource dependency research. Using set-theoretic operations—union, intersection, and complement—we examine how boundaries evolve when interdependence precedes and shapes ...
Symeon Mandrinos, Constance Liew Sat Lin
doaj   +1 more source

Home - About - Disclaimer - Privacy