Results 41 to 50 of about 174,525 (257)

Background risk model in presence of heavy tails under dependence

open access: yesNonlinear Analysis
In this paper, we examine two problems on applied probability, which are directly connected with the dependence in presence of heavy tails. The first problem is related to max-sum equivalence of the randomly weighted sums in bivariate setup. Introducing
Dimitrios G. Konstantinides   +1 more
doaj   +1 more source

Myxococcus xanthus DK1622 Coordinates Expressions of the Duplicate groEL and Single groES Genes for Synergistic Functions of GroELs and GroES

open access: yesFrontiers in Microbiology, 2017
Chaperonin GroEL (Cpn60) requires cofactor GroES (Cpn10) for protein refolding in bacteria that possess single groEL and groES genes in a bicistronic groESL operon.
Yue-zhong Li   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Interdependence in shared goal pursuit among established and impromptu dyads: Expectations, allocation, and performance

open access: yesFrontiers in Social Psychology
IntroductionTransactive goal dynamics theory asserts that interdependent partners have opportunities and motivation to learn about each other's idiosyncratic skills and interests in goal pursuit, producing enhanced system-level knowledge and performance.
Michelle R. vanDellen   +4 more
doaj   +1 more source

Vernacular Architecture: A Term Denoting and Transporting Diverse Content

open access: yesBuilt Heritage, 2019
A selective review of the literature demonstrates the difficulty in defining ‘vernacular architecture’. Recent studies have presented an overly narrow, single-sided, or even unacceptable image of the topic in comparison with many earlier definitions and ...
Klaus Zwerger
doaj   +1 more source

In search of an optimal parenting style [PDF]

open access: yesНациональный психологический журнал, 2019
Background. In modern psychology, the question is increasingly being raised if there is a fine type of upbringing or it is rather a myth that does not correspond to the reality of family education practices.
Olga A. Karabanova
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A woman-centred childbirth model

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2010
A model for woman-centred childbirth was developed through four phases in accordance with the objectives of the study, namely, a description of mothers’ experiences of childbirth and that of attending midwives of managing mothers during childbirth ...
Maria S. Maputle
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Considering geographies of interdependence in responsible innovation

open access: yesJournal of Responsible Innovation
In this Perspective piece, we forward a case for considering geographies of interdependence in understanding and implementing Responsible Innovation. At the core of this framing is an emphasis on how innovation occurring in specific places often depends ...
Dan Santos, Ehsan Nabavi
doaj   +1 more source

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