Results 51 to 60 of about 174,525 (257)

Reconceptualising Children’s Agency as Continuum and Interdependence

open access: yesSocial Sciences, 2019
Although the idea that children are social actors is well-recognised within childhood studies, the structural contexts shaping child agency and the everyday practices that manifest in children’s social relationships with other generations are not ...
Tatek Abebe
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Interdependence in urban systems: the urban consequences of the growth of higher education and research in Sweden

open access: yesDela, 2004
This study suggests that history may repeat itself, especially in the context of ideas as, for example, in the concept of interdependence in urban systems.
Olof Wärneryd
doaj   +1 more source

Interdependence

open access: yes
Interdependence is an interdisciplinary concept that encapsulates the careful, complex, and reciprocal relationships between (disabled and non-disabled) people, animals, technologies, and things.
Budworth, P., Larrington-Spencer, H.
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Rethinking love, independence, and speciesism in assistance dog discourse

open access: yesFrontiers in Sociology
This paper challenges the prevailing belief that assistance dogs inherently love their roles, arguing that the notion of “unconditional love” in discourses on assistance dog perpetuates a human-centric perspective and reinforces speciesism. It emphasizes
Birkan Taş
doaj   +1 more source

Analysis of linseed (Linum usitatissiumum L.) plant branching as related to variability and interdependence of traits

open access: yesActa Agrobotanica, 2013
Branching process of two linseed cultivars ('Hungarian Gold' and 'Opal') was analysed each year of vegetation between 1999 and 2002 characterised by different weather course.
Tadeusz Zając
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

The Roles of Object Relations, Paranoid Thoughts and Interdependence in the Stability of Married Women’s Life (Mashhad City) [PDF]

open access: yesمطالعات زن و خانواده
The present study was conducted with the aim of investigating the roles of object relations, paranoid thoughts and interdependence in the stability of married women’s life in Mashhad. This study was a descriptive correlational study.
Fateme Sadat Mortazavi Karimabad   +1 more
doaj   +1 more source

Home - About - Disclaimer - Privacy